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Review
. 2021 Mar 29;9(2):91-104.
doi: 10.1093/gastro/goab010. eCollection 2021 Apr.

Gastrointestinal cancers in China, the USA, and Europe

Yumo Xie  1   2 , Lishuo Shi  3 , Xiaosheng He  1   2 , Yanxin Luo  1   2
Affiliations
Review

Gastrointestinal cancers in China, the USA, and Europe

Yumo Xie et al. Gastroenterol Rep (Oxf). .

Abstract

Gastrointestinal (GI) cancers, including colorectal cancer, gastric cancer, and esophageal cancer, are a major medical and economic burden worldwide and have the largest number of new cancer cases and cancer deaths each year. Esophageal and gastric cancers are most common in developing countries, while colorectal cancer forms the major GI malignancy in Western countries. However, a great shift in the predominant GI-cancer type is happening in countries under economically transitioning and, at the same time, esophageal and gastric cancers are reigniting in Western countries due to the higher exposure to certain risk factors. The development of all GI cancers is highly associated with lifestyle habits and all can be detected by identified precancerous diseases. Thus, they are all suitable for cancer screening. Here, we review the epidemiological status of GI cancers in China, the USA, and Europe; the major risk factors and their distribution in these regions; and the current screening strategies.

Keywords: cancer screening; colorectal cancer; epidemiology; esophageal cancer; gastric cancer.

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Figures

Figure 1.
Figure 1.
Time trends of incidence rates of colorectal cancer in men and women across China, the USA, and Europe. Data from National Cancer Center (China), Centers for Disease Control and Prevention (the USA), and European Cancer Information System (EU).
Figure 2.
Figure 2.
Time trends of incidence rates of gastric cancer in men and women across China, the USA, and Europe. Data from National Cancer Center (China), Centers for Disease Control and Prevention (the USA), and European Cancer Information System (EU).
Figure 3.
Figure 3.
Time trends of incidence rates of esophageal cancer in men and women across China, the USA, and Europe. Data from National Cancer Center (China), Centers for Disease Control and Prevention (the USA), and European Cancer Information System (EU).
See this image and copyright information in PMC

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