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Review
. 2021 Dec;268(12):4908-4914.
doi: 10.1007/s00415-021-10618-2. Epub 2021 May 24.

Neurological update: cognitive rehabilitation in multiple sclerosis

Michelle H Chen  1   2 , Nancy D Chiaravalloti  1   2 , John DeLuca  3   4
Affiliations
Review

Neurological update: cognitive rehabilitation in multiple sclerosis

Michelle H Chen et al. J Neurol. 2021 Dec.

Abstract

Cognitive impairment is a common and debilitating symptom in multiple sclerosis (MS). There is limited evidence that disease-modifying therapies are effective in treating cognitive dysfunction. Cognitive rehabilitation is a promising approach to treat cognitive dysfunction in MS, gaining empirical support over the last 10 years. The current review will provide a brief overview of cognitive rehabilitation in MS. Overall, there is evidence that cognitive rehabilitation programs (either restorative or compensatory) are efficacious in treating MS-related cognitive dysfunction. Clinicians should consider this low-cost, low-risk, yet effective treatment approach for their patients.

Keywords: Cognitive impairment; Cognitive rehabilitation; Cognitive remediation; Multiple sclerosis.

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