Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Oct;58(10):1307-1327.
doi: 10.1007/s00592-021-01738-2. Epub 2021 May 24.

Prevalence of periodontitis in people clinically diagnosed with diabetes mellitus: a meta-analysis of epidemiologic studies

Mengwen Zheng  1 , Cheng Wang  2 , Ali Ali  3 , Yi An Shih  4 , Qinqin Xie  5 , Chao Guo  6   7
Affiliations
Review

Prevalence of periodontitis in people clinically diagnosed with diabetes mellitus: a meta-analysis of epidemiologic studies

Mengwen Zheng et al. Acta Diabetol. 2021 Oct.

Abstract

Aims: The relationship between diabetes mellitus and periodontitis has long been discussed, but the conclusion of this relationship was controversial. We conducted this meta-analysis to explore the association between diabetes mellitus and the prevalence of periodontitis.

Methods: PubMed, Embase, Web of Science, and the Cochrane Library were searched for studies reporting associations of periodontitis with diabetes. Gray literature was integrated from the Open-Gray database. Prevalence estimates and odds ratios were extracted by two independent reviewers and synthesized through meta-analyses.

Results: Twenty-seven papers met the inclusion criteria involving 3092 diabetic patients and 23,494 controls. Overall prevalence of periodontitis was 67.8% in diabetics (combined types) and 35.5% in patients without diabetes (OR, 1.85; 95%CI, 1.61-2.11). Probing depth (MD 0.23; 95% CI, 0.17-0.29; I2 = 25%) and plaque index (MD, 0.20; 95% CI, 0.18-0.23; P = 0.59; I2 = 0%) severity scores were significantly greater among the diabetic group.

Conclusions: The prevalence and severity of periodontitis are greater in patients with diabetes than in non-diabetic populations.

Keywords: Diabetes; Meta-analysis; Periodontitis; Prevalence; Probing depth.

PubMed Disclaimer

References

    1. Chamberlain JJ, Rhinehart AS, Shaefer CF Jr et al (2016) Diagnosis and management of diabetes: synopsis of the 2016 American diabetes association standards of medical care in diabetes. Ann Intern Med 164(8):542–552. https://doi.org/10.7326/m15-3016 - DOI - PubMed
    1. Zheng Y, Ley SH, Hu FB (2018) Global aetiology and epidemiology of type 2 diabetes mellitus and its complications. Nat Rev Endocrinol 14(2):88–98. https://doi.org/10.1038/nrendo.2017.151 - DOI - PubMed
    1. Ogurtsova K, da Rocha Fernandes JD, Huang Y et al (2017) IDF Diabetes Atlas: Global estimates for the prevalence of diabetes for 2015 and 2040. Diabetes Res Clin Pract 128:40–50. https://doi.org/10.1016/j.diabres.2017.03.024 - DOI - PubMed
    1. Kornman KS (2008) Mapping the pathogenesis of periodontitis: a new look. J Periodontol 79(8 Suppl):1560–1568. https://doi.org/10.1902/jop.2008.080213 - DOI - PubMed
    1. Albandar JM (2000) Global risk factors and risk indicators for periodontal diseases. Periodontol 2002(29):177–206

LinkOut - more resources