Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1988 Apr;26(4):199-203.

A study of the levels of tobramycin and gentamicin in human serum and renal cortex and of changes in in vitro bacterial sensitivity

E Faragó  1 , T Guba
Affiliations
  • PMID: 3403098

A study of the levels of tobramycin and gentamicin in human serum and renal cortex and of changes in in vitro bacterial sensitivity

E Faragó et al. Int J Clin Pharmacol Ther Toxicol. 1988 Apr.

Abstract

Concentration of gentamicin and tobramycin in sera and renal tissue was determined. Though between the 2nd and 6th day of the treatment, gentamicin cumulated in the renal tissue, but it did not reach toxic value. Tobramycin did not show cumulation tendency. According to in vitro bacterium sensitivity studies, the wide scale use of tobramycin in the clinical practice caused the sudden increase of resistance. To avoid this, the rules of antibiotic treatment should be observed.

PubMed Disclaimer