[Risk factors for urolithiasis]
- PMID: 34032133
- DOI: 10.1024/0040-5930/a001264
[Risk factors for urolithiasis]
Abstract
Risk factors for urolithiasis Abstract. The prevalence and incidence of kidney stones has continuously increased over the last years. Recent evidence suggests that kidney stones have a substantial morbidity including chronic kidney disease and end stage kidney disease as well as significantly increased risk for cardiovascular diseases. Thus, risk stratification - especially of high-risk patients - is mandatory in the management of kidney stone patients. There is a huge variety in risk factors for nephrolithiasis including general factors (such as young age at manifestation, familial disposition), genetic or acquired diseases with risk of stone formation, drugs etc. Several prediction scores have been developed to assess recurrence risk in kidney stone formers. However, only very few studies have investigated these tools and more evidence is needed in future to proof if these scores reliably predict stone recurrence risk.
Zusammenfassung. Trotz zunehmender Fortschritte in der Medizin sind die Prävalenz und Inzidenz von Nierensteinen in den letzten Jahren kontinuierlich angestiegen. Nierensteine sind mit einem hohen Rezidivrisiko, einer hohen Morbidität inklusive Entwicklung einer chronischen Niereninsuffizienz und Dialysepflichtigkeit sowie einem erhöhten kardiovaskulären Risiko assoziiert. Daher ist das Erkennen von Risikofaktoren und insbesondere Hochrisikopatienten für das Management von Nierensteinpatienten essenziell. Die Risikofaktoren für Nierensteinbildung sind vielfältig und bestehen unter anderem aus allgemeinen Faktoren (junges Manifestationsalter, familiäre Disposition), genetische oder erworbene Erkrankungen mit Risiko für Steinbildung, Medikamente etc. In diesem Rahmen wurden auch verschiedene Prädiktions-Scores für die Abschätzung des Rezidivrisikos entwickelt. Für den Nutzen des Einsatzes dieser Tools ist jedoch noch nicht genügend Evidenz vorhanden.
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