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. 2021 May 25;22(1):195.
doi: 10.1186/s12882-021-02383-1.

Analysis of chronic kidney disease among national hospitalization data with 14 million children

Xinmiao Shi  1 , Ying Shi  2 , Luxia Zhang  3   4 , Lanxia Gan  2 , Xuhui Zhong  1 , Yuming Huang  3 , Chen Yao  5   6 , Yanfang Wang  6 , Chongya Dong  5 , Beini Liu  1 , Fang Wang  1 , Haibo Wang  7   8 , Jie Ding  9
Affiliations

Analysis of chronic kidney disease among national hospitalization data with 14 million children

Xinmiao Shi et al. BMC Nephrol. .

Abstract

Background: The main purpose was to determine basic epidemiological data on CKD among hospitalized pediatric patients in China.

Methods: Data from pediatric inpatients with CKD hospitalized from June 1, 2013 to May 31, 2017 were extracted from the electronic records of HQMS database, which includes over 14 million inpatients. Codes from the 10th revision of the International Classification of Diseases (ICD-10) were used to search the database.

Results: A total of 524 primary diseases of CKD were included in this study. In all, there were 278 231 pediatric inpatients with CKD, which accounted for 1.95 % of the 14 250 594 pediatric inpatients registered in the HQMS database. The number of pediatric inpatients with CKD was 67 498 in 2013, 76 810 in 2014, 81 665 in 2015 and 82 649 in 2016, which accounted for 1.93 %, 1.93 %, 1.99 and 2.09 %, respectively, of the total population of pediatric inpatients. The etiology of CKD was secondary nephrosis in 37.95 % of cases, which ranked first and followed by CAKUT with a percentage of 24.61 %. Glomerular diseases and cystic kidney disease accounted for 21.18 and 5.07 %, respectively. Among all 278 231 patients, 6 581 (2.37 %) had a primary discharge diagnosis of CKD. The renal pathology findings of CKD showed that IgA accounted for 51.17 %.

Conclusions: This study provides a descriptive analysis of the hospitalized population of pediatric CKD patients. Our study provides important, fundamental data for policy making and legislation, registry implementation and the diagnosis, treatment and prevention of CKD in China.

Keywords: Child; Chronic kidney disease; Database; Hospitalization.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Flowchart of study
Fig. 2
Fig. 2
Number and proportion of pediatric CKD patients among all childhood inpatients
Fig. 3
Fig. 3
Etiology of CKD
Fig. 4
Fig. 4
Renal biopsy frequencies of CKD
Fig. 5
Fig. 5
Number and proportion of pediatric CKD-label patients
Fig. 6
Fig. 6
Proportion of each CKD stage among CKD-label patients
Fig. 7
Fig. 7
Etiology of CKD among CKD-label patients
See this image and copyright information in PMC

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