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. 2021 May 25;7(1):41.
doi: 10.1186/s40942-021-00312-w.

Unilateral acute posterior multifocal placoid pigment epitheliopathy in a convalescent COVID-19 patient

Francisco Olguín-Manríquez  1   2 , Linda Cernichiaro-Espinosa  3 , Arturo Olguín-Manríquez  4 , Rebeca Manríquez-Arias  5 , Erick Omar Flores-Villalobos  6 , Perla Ayumi Kawakami-Campos  7
Affiliations

Unilateral acute posterior multifocal placoid pigment epitheliopathy in a convalescent COVID-19 patient

Francisco Olguín-Manríquez et al. Int J Retina Vitreous. .

Abstract

Background: To report a case of unilateral acute posterior multifocal placoid pigment epitheliopathy (APMPPE) in a Hispanic convalescent COVID-19 female patient. Case presentation A 35-year-old Hispanic female with exposure to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was evaluated due to unilateral visual loss. Ophthalmic examination and diagnostic tests were consistent with APMPPE.

Discussion: Ocular changes can be observed in patients with COVID-19. A complete ophthalmic evaluation must be performed in patients with low vision after SARS-CoV-2 infection.

Keywords: Acute posterior multifocal placoid pigment epitheliopathy; Coronavirus disease 2019; Severe acute respiratory syndrome coronavirus 2.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Figure. 1
Figure. 1
Fundus multimodal imaging of a patient with serological evidence of SARS-CoV-2 exposure. A, B: color fundus photographs showing multiple yellow–white placoid lesions involving the fovea in the right eye. Left eye posterior segment is unremarkable. C–D: fluorescein angiography demonstrates early hypofluorescence with hyperfluorescent staining of all lesions. E: normal fluorescein angiogram in the LE. F: fundus autofluorescence showing hypoautofluorescent lesions surrounded by a hyperautofluorescent halo in the right eye. G: fundus autofluorescence shows isoautofluorescence in the left eye. H–I: cross-sectional optical coherence tomography (OCT) scans in extrafoveal lesions demonstrate hyper-reflective material at the level of the outer retinal layers. Disruption of the interdigitation zone and hyper-reflective material is observed at the foveal depression
See this image and copyright information in PMC

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