Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Apr 15;11(2):173-178.
doi: 10.4103/jispcd.JISPCD_420_20. eCollection 2021 Mar-Apr.

Effect of Zamzam Water on Microhardness of Primary Tooth Enamel After Erosion Induced by Claritin Syrup: An In-vitro Study

Affiliations

Effect of Zamzam Water on Microhardness of Primary Tooth Enamel After Erosion Induced by Claritin Syrup: An In-vitro Study

Aseel Khalid Kufiyah et al. J Int Soc Prev Community Dent. .

Abstract

Background: Dental erosion is an irreversible damage to hard tissues in the mouth due to acid dissolution not induced by microorganisms. Oral medications contributed to the etiology of dental erosion. Among these medications, antihistamine-containing syrups were reported to have a considerable erosive effect on hard dental tissues.

Objective: The objective was to evaluate the effect of Zamzam water on the microhardness of primary tooth enamel after erosion induced by Claritin™ syrup.

Materials and methods: The present in-vitro study was conducted on 25 primary central incisor teeth. The labial surfaces of the specimens were prepared for microhardness testing. Baseline microhardness was measured first, then the samples were submerged in the erosive agent Claritin™ syrup, for 30 min every 12 h for 12 days. Thereafter, all the teeth were placed in Zamzam water for 30 min every 12 h for 12 days. The microhardness was measured by the Vickers hardness tester and expressed as Vickers microhardness value (VH). The measurements were completed three times for the same sample: baseline, after erosion, and after Zamzam treatment. Data were analyzed statistically using one-way repeated analysis of variance (ANOVA) followed by Tukey's post hoc test.

Results: The primary teeth included in this study showed a significant increase in their surface microhardness after Zamzam water treatment; the mean value of VH was increased from 33.12 ± 1.62 to 89.32 ± 8.52 (P-value <0.0001).

Conclusion: Zamzam water could be introduced as a part of the management of dental erosion in the primary dentition.

Keywords: Antihistamine; Zamzam water; dental erosion; microhardness; remineralization.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflicts of interest, financial or otherwise.

Figures

Figure 1
Figure 1
An image of baseline Vickers hardness indentation
Figure 2
Figure 2
An image of after-erosion Vickers hardness indentation
Figure 3
Figure 3
An image of after-Zamzam Vickers hardness indentation

Similar articles

Cited by

References

    1. Daly B, Newton JT, Fares J, Chiu K, Ahmad N, Shirodaria S, et al. Dental tooth surface loss and quality of life in university students. Prim Dent Care. 2011;18:31–5. - PubMed
    1. Da Silva Pierro VS, Furtado BR, Villardi M, Cabral LM, Eduardo Moreira Silva EM, Maia CL. Erosive effect of an antihistamine liquid formulation on bovine teeth: Influence of exposure time. Braz J Oral Sci. 2010;9:20–4.
    1. Magalhães AC, Wiegand A, Rios D, Honório HM, Buzalaf MA. Insights into preventive measures for dental erosion. J Appl Oral Sci. 2009;17:75–86. - PMC - PubMed
    1. Costa CC, Almeida IC, Costa Filho LC. Erosive effect of an antihistamine-containing syrup on primary enamel and its reduction by fluoride dentifrice. Int J Paediatr Dent. 2006;16:174–80. - PubMed
    1. Gaber AM, Dowidar KM, Talaat DM. The effect of Ccp-Acp on the surface microhardness of primary tooth enamel eroded by antihistamine syrup (in vitro study) Alexandria Dent J. 2016;41:86–91.