An official website of the United States government
The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before
sharing sensitive information, make sure you’re on a federal
government site.
The site is secure.
The https:// ensures that you are connecting to the
official website and that any information you provide is encrypted
and transmitted securely.
Perioperative bleeding is one of the major comorbidities associated with surgery. While anesthesia is a critical component to perform surgery, a number of clinical studies supported the contribution of anesthetic drugs to perioperative bleeding. Here, we reviewed the literature on this topic including the underlying mechanism and discussed the future direction on coagulation research in anesthesia.
The authors declare that they have no conflicts of interest.
References
Faraday N. Platelets, perioperative hemostasis, and anesthesia. Anesthesiology. 2002;96(5):1042–1043. doi: 10.1097/00000542-200205000-00003.
-
DOI
-
PubMed
Ueda I. The effects of volatile general anesthetics on adenosine diphosphate-induced platelet aggregation. Anesthesiology. 1971;34(5):405–408. doi: 10.1097/00000542-197105000-00006.
-
DOI
-
PubMed
Ahn H. J., Chung S. K., Dhong H. J., et al. Comparison of surgical conditions during propofol or sevoflurane anaesthesia for endoscopic sinus surgery. British Journal of Anaesthesia. 2008;100(1):50–54. doi: 10.1093/bja/aem304.
-
DOI
-
PubMed
Pavlin J. D., Colley P. S., Weymuller E. A., Jr., Van Norman G., Gunn H. C., Koerschgen M. E. Propofol versus isoflurane for endoscopic sinus surgery. American Journal of Otolaryngology. 1999;20(2):96–101. doi: 10.1016/S0196-0709(99)90018-2.
-
DOI
-
PubMed
Blackwell K. E., Ross D. A., Kapur P., Calcaterra T. C. Propofol for maintenance of general anesthesia: a technique to limit blood loss during endoscopic sinus surgery. American Journal of Otolaryngology. 1993;14(4):262–266. doi: 10.1016/0196-0709(93)90072-F.
-
DOI
-
PubMed