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. 2021;3(8):1704-1706.
doi: 10.1007/s42399-021-00964-7. Epub 2021 May 20.

Long-COVID Headache

Paolo Martelletti  1   2   3 , E Bentivegna  3   4 , V Spuntarelli  3   5 , M Luciani  3   6
Affiliations

Long-COVID Headache

Paolo Martelletti et al. SN Compr Clin Med. 2021.

Abstract

The so-called long COVID-19 is a set of symptoms that accompanies the patient even for months after discharge from the hospital. These symptoms include easy muscle fatigue, moderate breathlessness, persistent headache, the feeling of a foggy head, and the development of psychiatric disorders. In general, the quality of life of at least half of the patients who come out of the COVID-19 syndrome, both mild and severe, shows a markedly worsening despite having passed a difficult physical and psychological test. Among all the neurological disorders that can most frequently be found in the long COVID-19, it is important to consider the persistent headache symptomatology as a possible chronic sequela of the infection. Since there is not a definition in the International Headache Society classification of this type of headache, we must focus our attention on this long-COVID-19 headache especially because clinical studies are being planned to collect big data for the International Headache Society Classification Committee.

Keywords: Classification; Long-Covid-19; Neurological sequalae; Pain; Peristent headache.

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Conflict of interest statement

Conflict of InterestThe authors declare no competing interests.

References

    1. Martelletti P, Bentivegna E, Luciani M, Spuntarelli V. Headache as a prognostic factor for COVID-19. Time to re-evaluate. SN Compr Clin Med. 2020;26:1–2. doi: 10.1007/s42399-020-00657-7. - DOI - PMC - PubMed
    1. Howard LM, Garguilo K, Gillon J, Seegmiller AC, Schmitz JE, Webber SA, Banerjee R. Characteristics and clinical features of SARS-CoV-2 infections among ambulatory and hospitalized children and adolescents in an integrated health care system in Tennessee. medRxiv [Preprint]. 2020 13:2020. 10.1101/2020.10.08.20208751.
    1. Pullen MF, Skipper CP, Hullsiek KH, Bangdiwala AS, Pastick KA, Okafor EC, Lofgren SM, Rajasingham R, Engen NW, Galdys A, Williams DA, Abassi M, Boulware DR. Symptoms of COVID-19 outpatients in the United States. Open Forum Infect Dis. 2020;7(7):ofaa271. doi: 10.1093/ofid/ofaa271. - DOI - PMC - PubMed
    1. Spuntarelli V, Luciani M, Bentivegna E, Marini V, Falangone F, Conforti G, Rachele ES, Martelletti P. COVID-19: is it just a lung disease? A case-based review. SN Compr Clin Med. 2020;28:1–6. doi: 10.1007/s42399-020-00418-6. - DOI - PMC - PubMed
    1. Pennica A, Conforti G, Falangone F, Martocchia A, Tafaro L, Sentimentale A, Marini V, Pezzuto A, Spuntarelli V, Martelletti P. Clinical management of adult coronavirus infection disease 2019 (COVID-19) positive in the setting of low and medium intensity of care: a short practical review. SN Compr Clin Med. 2020;29:1–6. doi: 10.1007/s42399-020-00333-w. - DOI - PMC - PubMed

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