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Review
. 2021 Jul;23(4):349-359.
doi: 10.1007/s40272-021-00454-2. Epub 2021 May 26.

Lidocaine Infusions for Pain Management in Pediatrics

Elizabeth A Hall  1 , Hannah E Sauer  2 , Margaret S Davis  3 , Doralina L Anghelescu  4
Affiliations
Review

Lidocaine Infusions for Pain Management in Pediatrics

Elizabeth A Hall et al. Paediatr Drugs. 2021 Jul.

Abstract

Lidocaine is an amino amide with a well-established role as a local anesthetic agent. Systemic intravenous administration expands its clinical use to include acute and chronic pain circumstances, such as postoperative pain, neuropathic pain, postherpetic neuralgia, hyperalgesia, visceral pain, and centrally mediated pain. For refractory pain that has not responded to conventional therapy or if further escalation of treatment is prevented by contraindications or side effects to standard therapies, a continuous infusion of lidocaine may be considered as a single intervention or as a sequence of infusions. Here, we review and evaluate published data reflecting the use of lidocaine continuous infusions for pain management in the pediatric population.

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Conflict of interest statement

Conflict of Interest Elizabeth A. Hall, Hannah E. Sauer, Margaret S. Davis, and Doralina L. Anghelescu declare that they have no conflict of interest.

Figures

Figure 1.
Figure 1.
Signs and symptoms of lidocaine toxicity relative to lidocaine serum concentrations.
See this image and copyright information in PMC

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