Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Observational Study
. 2021 Nov;131(11):E2749-E2754.
doi: 10.1002/lary.29667. Epub 2021 Jun 5.

COVID-19 Cross-Infection Rate After Surgical Procedures: Incidence and Outcome

Affiliations
Observational Study

COVID-19 Cross-Infection Rate After Surgical Procedures: Incidence and Outcome

Bassem Mettias et al. Laryngoscope. 2021 Nov.

Abstract

Objectives/hypothesis: Severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) is transmitted by droplet as well as airborne infection. Surgical patients are vulnerable to the infection during their hospital admission. Some surgical procedures are classified as aerosol generating (AGP).

Study design: Retrospective observational study of four specialties associates with known AGP's during the 4 months of the first wave of UK COVID-19 epidermic to identify post-surgical cross-infection with SARSCoV-2 within 14 days of a procedure.

Methods: Retrospective observational study in a tertiary healthcare center of four specialties associates with known AGP's during the 4 months of the first wave of UK COVID-19 epidermic to identify post-surgical cross-infection with SARSCoV-2 within 14 days of a procedure.

Results: There were 3,410 procedures reported during this period. The overall cross-infection rate from tested patients was 1.3% (4 patients), that is, 0.11% of all operations over 4 months. Ear, nose, and throat carried slightly higher rate of infection (0.4%) than gastroenterology (0.08%). The mortality rate was 0.3% (one gastroenterology patient from 304 positive cases) compared to 0% if surgery performed after recovery from SARSCoV-2 and 37.5% when surgery was conducted during the incubation period of the disease. Routine preoperative rapid screening tests and self-isolation are crucial to avoid the risk of cross-infection. Patients with underlying malignancy or receiving chemotherapy were more prone to pulmonary complications and mortality.

Conclusion: The risk of SARS-COV-2 cross-infection after surgical procedure is very low. Preoperative screening and self-isolation together with personal protective measures should be in place to minimize the cross-infection.

Level of evidence: 4 Laryngoscope, 131:E2749-E2754, 2021.

Keywords: SARSCoV-2; mortality; outcome; surgery.

PubMed Disclaimer

Figures

Fig 1
Fig 1
Flow chart of patient distribution in the study.
Fig 2
Fig 2
Correlation between hospital and community for admission and mortality.
Fig 3
Fig 3
Correlation between co‐morbidities and outcome.

References

    1. WHO Director‐General's opening remarks at the media briefing on COVID‐19 ‐ 11 March 2020. Available at: https://www.who.int/director-general/speeches/detail/who-director-genera.... Accessed March 21, 2021.
    1. Docherty AB, Harrison EM, Green CA, et al. Features of 20 133 UKpatients in hospital with covid‐19 using the ISARIC WHO clinical characterisation protocol: prospective observational cohort study. BMJ 2020;369:m1985. - PMC - PubMed
    1. Jackson T, Deibert D, Wyatt G, et al. Classification of aerosol‐generating procedures: a rapid systematic review. BMJ Open Respir Res 2020;7:e000730. 10.1136/bmjresp-2020-000730. - DOI - PMC - PubMed
    1. The Lancet Respiratory Medicine . COVID‐19 transmission‐up in the air. Lancet Respir Med 2020;8:1159. 10.1016/S2213-2600(20)30514-2. - DOI - PMC - PubMed
    1. COVIDSurg Collaborative . Head and neck cancer surgery during the COVID‐19 pandemic: an international, multicenter, observational cohort study. Cancer 2020;21. 10.1002/cncr.33320. - DOI - PubMed

Publication types

MeSH terms