Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Apr 27;16(1):27.
doi: 10.5334/gh.960.

Considerations and Guidance for the Structure, Organisation, and Operation of Cardiometabolic Prevention Units: A Consensus Statement of the Inter-American Society of Cardiology

Affiliations

Considerations and Guidance for the Structure, Organisation, and Operation of Cardiometabolic Prevention Units: A Consensus Statement of the Inter-American Society of Cardiology

Carlos I Ponte-Negretti et al. Glob Heart. .

Abstract

Cardiovascular diseases (CVDs) remain the leading cause of death worldwide, particularly in low- and middle-income regions such as Latin America. This is because of the combination and interaction in different proportions of a high prevalence of cardiometabolic risk factors and socio-economic and cultural characteristics. This reality brings about the need to change paradigms to consistently and systematically boost cardiovascular prevention as the most cost-effective medium- to long-term strategy to reduce their prevalence in medium- and low-resource countries, not only in Latin America but also in other global regions. To achieve the therapeutic goals in various diseases, including CVD, the current literature demonstrates that the most effective way is to carry out the patient's diagnosis and treatment in multidisciplinary units. For this reason, the Inter American Society of Cardiology (IASC) proposes the creation of cardiometabolic prevention units (CMPUs) as a regional initiative exportable throughout the world to standardise cardiovascular prevention based on the best available evidence. This ensures homogeneity in the global management of cardiometabolic risk factors and access to quality medicine independently of the population's social situation. These guidelines, written by a panel of experts in cardiovascular prevention, defines what a CMPU is, its objectives and the minimum requirements for it, as well as proposing three categories and suggesting an operational scheme. It must be used as a guide for all individuals or centres that, aware of the need for multidisciplinary and standardised work, want to create a unit for the comprehensive management of cardiometabolic risk established as an international research network. Lastly, the document makes meaningful points on the determination of cardiovascular risk and its importance. These guidelines do not cover specific targets and therapeutic schemes, as these topics will be extensively discussed in another SIAC publication, namely a statement on residual cardiometabolic risk.

Keywords: cardiometabolic prevention unit; cardiometabolic risk; cardiovascular prevention.

PubMed Disclaimer

Conflict of interest statement

P.L-J. received speaker honoraria from Ferrer, Menarini, and Abbott. A.L. has been a consultant to Amgen, Pfizer, Raffo, Kowa, Gador, and PTC; received speaker honoraria from Amgen, Baliarda, Raffo, Sanofi, Pfizer, and PTC; and received research grants from Amgen, Resverlogix, Esperion, and Novonordisk. C.I.P-N. received speaker honoraria from Ferrer outside the content of this manuscript. E. R. is an employee in the Medical Department in Ferrer Laboratories. F.S.W., D.P., F.L., A.S.L., L.M., E.B., J.R.G-M., R.L., O.V., L.C., A.P., and G.B. have no competing interests to declare.

Figures

Figure 1
Figure 1
Diagram of the relationship between the socioeconomic status and the development of cardiometabolic conditions. Footnote: AD, atherogenic dyslipidemia; CMR, cardiometabolic risk; HT, hypertension; T2DM, type 2 diabetes mellitus.
Figure 2
Figure 2
Diagram of the fundamental steps and periodical evaluations to be performed by cardiometabolic units. Footnote: AD, atherogenic dyslipidemia; CMR, cardiometabolic risk; HT, hypertension; OB, obesity; T2DM type 2 Diabetes Mellitus.

References

    1. World Health Organization (WHO). Global Atlas on Cardiovascular Disease Prevention and Control. Mendis S, Puska P, Norrving B (eds.) Geneva: 2011. Available from: https://www.who.int/cardiovascular_diseases/publications/atlas_cvd/en/ (accessed Jul 2020).
    1. Dagenais GR, Leong DP, Rangarajan S, et al. Variations in common diseases, hospital admissions, and deaths in middle-aged adults in 21 countries from five continents (PURE): A prospective cohort study. Lancet. 2020; 395: 785–94. DOI: 10.1016/S0140-6736(19)32007-0 - DOI - PubMed
    1. Libby P, Buring JE, Badimon L, et al. Atherosclerosis. Nat Rev Dis Primers. 2019; 5: 56. DOI: 10.1038/s41572-019-0106-z - DOI - PubMed
    1. Yusuf S, Hawken S, Ounpuu S, et al. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. Lancet. 2004; 364: 937–52. DOI: 10.1016/S0140-6736(04)17018-9 - DOI - PubMed
    1. O’Donnell MJ, Chin SL, Rangarajan S, et al. Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE): A case-control study. Lancet. 2016; 388: 761–75. DOI: 10.1016/S0140-6736(16)30506-2 - DOI - PubMed

Publication types

LinkOut - more resources