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. 2021 May 14:36:107147.
doi: 10.1016/j.dib.2021.107147. eCollection 2021 Jun.

Processed HIV prognostic dataset for control experiments

Moses E Ekpenyong  1   2 , Philip I Etebong  1 , Tenderwealth C Jackson  3 , Edidiong J Udofa  3
Affiliations

Processed HIV prognostic dataset for control experiments

Moses E Ekpenyong et al. Data Brief. .

Abstract

This paper provides a control dataset of processed prognostic indicators for analysing drug resistance in patients on antiretroviral therapy (ART). The dataset was locally sourced from health facilities in Akwa Ibom State of Nigeria, West Africa and contains 14 attributes with 1506 unique records filtered from 3168 individual treatment change episodes (TCEs). These attributes include sex, before and follow-up CD4 counts (BCD4, FCD4), before and follow-up viral load (BRNA, FRNA), drug type/combination (DTYPE), before and follow-up body weight (Bwt, Fwt), patient response to ART (PR), and classification targets (C1-C5). Five (5) output membership grades of a fuzzy inference system ranging from very high interaction to no interaction were constructed to model the influence of adverse drug reaction (ADR) and subsequently derive the PR attribute (a non-fuzzy variable). The PR attribute membership clusters derived from a universe of discourse table were then used to label the classification targets as follows: C1=no interaction, C2=very low interaction, C3=low interaction, C4=high interaction, and C5=very high interaction. The classification targets are useful for building classification models and for detecting patients with ADR. This data can be exploited for the development of expert systems, for useful decision support to treatment failure classification [1] and effectual drug regimen prescription.

Keywords: Adverse drug reaction; Antiretroviral therapy; HIV control data; Treatment change episode; Treatment failure classification.

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Conflict of interest statement

Moses Ekpenyong was funded by a research grant on drug-drug combination in treatment-enable patients on antiretroviral therapy by the Tertiary Education Trust Fund (TETFund), Nigeria. The authors declare that they have no known competing financial interests or personal relationships which have or could be perceived to have influenced the work reported in this article.

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