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Review
. 2021 May 1;40(5S):S26-S30.
doi: 10.1097/INF.0000000000002859.

Perinatal Infections With Ureaplasma

Kim Stol  1 , Jop Jans  2 , Lisa Ott de Bruin  2 , Wendy Unger  3 , Annemarie van Rossum  1
Affiliations
Review

Perinatal Infections With Ureaplasma

Kim Stol et al. Pediatr Infect Dis J. .

Abstract

Ureaplasma species are increasingly recognized as relevant pathogens in prenatal, perinatal and postnatal morbidity. They are commonly found as commensals on the mucous membranes of the lower urogenital tract of pregnant women, but when ascending, they can cause bacterial vaginosis, chorioamnionitis, premature birth and postnatal morbidities such as bronchopulmonary dysplasia, and early-onset neonatal sepsis and meningitis. The detection of Ureaplasma species is challenging and is not covered by routine diagnostics, and current empiric antibiotic treatment in neonates suspected of infection is not directed against Ureaplasma species. The aim of this review is to discuss the pathophysiology of Ureaplasma infections, the clinical consequences and the current difficulties in diagnosis and treatment by providing an overview of the current literature.

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Conflict of interest statement

The authors have no funding or conflicts of interest to disclose.

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