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Review
. 2021 Aug:49:52-57.
doi: 10.1016/j.coviro.2021.04.008. Epub 2021 May 4.

SARS-CoV-2 vaccines - the biggest medical research project of the 21st century

Drishya Kurup  1 , Matthias J Schnell  2
Affiliations
Review

SARS-CoV-2 vaccines - the biggest medical research project of the 21st century

Drishya Kurup et al. Curr Opin Virol. 2021 Aug.

Abstract

SARS-CoV-2 has been detected in more than 141 million people and caused more than 3 million deaths worldwide. To reduce the additional loss of millions of lives until natural immunity is reached, researchers have focused on the only known method to stop the COVID-19 pandemic: vaccines. The pandemic has propelled high-speed vaccine development, some based on novel technology previously not utilized in the vaccine field. The new technology opens new possibilities and comes with challenges because the long-term performance of the new platforms is unknown. Here we review the current leading vaccine candidates against COVID-19 and outline the advantages and disadvantages as well as the unknowns of each candidate.

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