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Case Reports
. 2021 May 28;14(5):e241037.
doi: 10.1136/bcr-2020-241037.

Disseminated Mycobacterium simiae and Mycobacterium avium infection causing an immune reconstitution inflammatory syndrome in a female patient with HIV infection

Jacqueline Alexandra Bachofner  1 , Kristian Ikenberg  2 , Bettina Schulthess  3 , Johannes Nemeth  4
Affiliations
Case Reports

Disseminated Mycobacterium simiae and Mycobacterium avium infection causing an immune reconstitution inflammatory syndrome in a female patient with HIV infection

Jacqueline Alexandra Bachofner et al. BMJ Case Rep. .

Abstract

This case study discusses the management of a disseminated Mycobacterium simiae and Mycobacterium avium infection causing an immune reconstitution inflammatory syndrome in a 52-year-old woman with HIV infection. Disseminated M. avium infections have extensively been described in HIV patients; however, reports of infections with M. simiae are rare. Treatment of M. simiae infections is challenging due to its high rates of natural drug resistances, and thus far, no standard treatment regimen exists.

Keywords: HIV / AIDS; infections; infectious diseases.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Cell block preparation from the fine needle aspiration (FNA) of an inguinal lymph node: granulomatous inflammation with typical aggregation of epithelioid histiocytes (H&E stain; 400×).
See this image and copyright information in PMC

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References

    1. Inderlied CB, Kemper CA, Bermudez LE. The Mycobacterium avium complex. Clin Microbiol Rev 1993;6:266–310. 10.1128/CMR.6.3.266 - DOI - PMC - PubMed
    1. Daley CL, Winthrop KL. Mycobacterium avium complex: addressing gaps in diagnosis and management. J Infect Dis 2020;222:S199–211. 222(Supplement_4). 10.1093/infdis/jiaa354 - DOI - PMC - PubMed
    1. Karassova V, Weissfeiler J, Krasznay E. Occurrence of atypical mycobacteria in Macacus rhesus. Acta Microbiol Acad Sci Hung 1965;12:275–82. - PubMed
    1. Hamieh A, Tayyar R, Tabaja H, et al. . Emergence of Mycobacterium simiae: A retrospective study from a tertiary care center in Lebanon. PLoS One 2018;13:e0195390. 10.1371/journal.pone.0195390 - DOI - PMC - PubMed
    1. Mortazavi Z, Bahrmand A, Sakhaee F, et al. . Evaluating the clinical significance of nontuberculous mycobacteria isolated from respiratory samples in Iran: an often overlooked disease. Infect Drug Resist 2019;12:1917–27. 10.2147/IDR.S214181 - DOI - PMC - PubMed

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