Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 May;171(1):1-14.
doi: 10.1007/s10517-021-05161-z. Epub 2021 May 29.

Induced Cell Death as a Possible Pathway of Antimutagenic Action

N V Eremina  1 , A K Zhanataev  1 , A D Durnev  2
Affiliations

Induced Cell Death as a Possible Pathway of Antimutagenic Action

N V Eremina et al. Bull Exp Biol Med. 2021 May.

Abstract

The existing concepts of antimutagenesis are briefly reviewed. Published reports on antimutagenic and proapoptotic properties of some polyphenols and compounds of other chemical groups obtained in representative in vitro and in vivo experiments on eukaryotic test systems are discussed. The relationships between the antimutagenic and proapoptotic properties of the analyzed compounds (naringin, apigenin, resveratrol, curcumin, N-acetylcysteine, etc.) are considered in favor of the hypothesis on induced cell death as an antimutagenic tool.

Keywords: antimutagenesis; antimutagens; cell death; mutagenesis.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Durnev AD. Antimutagenesis and antimutagens. Human Physiology. 2018;44(3):336-355. - DOI
    1. Durnev AD. Mutagens and antimutagens in food. Russ. J. Genetics. 1997;33(2):117-127.
    1. Pligina KL, Zhanataev AK, Kulakova AV, Chaika ZV, Durnev AD. Influence of acetylcysteine on cytogenetic effects of etoposide in mouse oocytes. Russ. J. Genetics. 2016;52(2):188- 193. - DOI
    1. Puzakov KK, Durnova NA, Ryzhenkova IG. Modern ideas about the effect of exogenous antioxidants on the growth of malignant tumors. Obzory po Klin. Farmakol. Lek. Ter. 2019;17(2):29-33. Russian. - DOI
    1. Abraham SK, Khandelwal N, Hintzsche H, Stopper H. Antigenotoxic effects of resveratrol: assessment of in vitro and in vivo response. Mutagenesis. 2016;31(1):27-33. doi: https://doi.org/10.1093/mutage/gev048 - DOI - PubMed

LinkOut - more resources