Is it the end of mouthwash as an intervention for gonorrhoea?

Eric P F Chow¹, Christopher K Fairley²

Affiliations

¹ Melbourne Sexual Health Centre, Alfred Health, Melbourne, VIC 3053, Australia; Central Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, VIC, Australia; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, VIC, Australia. Electronic address: eric.chow@monash.edu.
² Melbourne Sexual Health Centre, Alfred Health, Melbourne, VIC 3053, Australia; Central Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, VIC, Australia.

PMID: 34051184
DOI: 10.1016/S1473-3099(21)00195-X

Comment

Is it the end of mouthwash as an intervention for gonorrhoea?

Eric P F Chow et al. Lancet Infect Dis. 2021 Jun.

. 2021 Jun;21(6):763-764.

doi: 10.1016/S1473-3099(21)00195-X.

Authors

Eric P F Chow¹, Christopher K Fairley²

Affiliations

¹ Melbourne Sexual Health Centre, Alfred Health, Melbourne, VIC 3053, Australia; Central Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, VIC, Australia; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, VIC, Australia. Electronic address: eric.chow@monash.edu.
² Melbourne Sexual Health Centre, Alfred Health, Melbourne, VIC 3053, Australia; Central Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, VIC, Australia.

PMID: 34051184
DOI: 10.1016/S1473-3099(21)00195-X

No abstract available

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Conflict of interest statement

EPFC and CKF are investigators in the OMEGA trial. The OMEGA trial was funded by a National Health and Medical Research Council (NHMRC) project grant (GNT1122514). EPFC is supported by an Australian NHMRC Emerging Leadership investigator grant (GNT1172873). CKF is supported by an Australian NHMRC Leadership investigator grant (GNT1172900). We thank Ei Aung and Elena Rodriguez at the Melbourne Sexual Health Centre (Melbourne, VIC, Australia) for their assistance in assessing the risk of bias for the included studies.

Comment on

Antiseptic mouthwash for gonorrhoea prevention (OMEGA): a randomised, double-blind, parallel-group, multicentre trial.
Chow EPF, Williamson DA, Hocking JS, Law MG, Maddaford K, Bradshaw CS, McNulty A, Templeton DJ, Moore R, Murray GL, Danielewski JA, Wigan R, Chen MY, Guy RJ, Zhang L, Donovan B, Grulich AE, Kaldor JM, Whiley DM, Cornelisse VJ, Howden BP, Lewis DA, Read TRH, Fairley CK. Chow EPF, et al. Lancet Infect Dis. 2021 May;21(5):647-656. doi: 10.1016/S1473-3099(20)30704-0. Epub 2021 Mar 4. Lancet Infect Dis. 2021. PMID: 33676595 Clinical Trial.
Antibacterial mouthwash to prevent sexually transmitted infections in men who have sex with men taking HIV pre-exposure prophylaxis (PReGo): a randomised, placebo-controlled, crossover trial.
Van Dijck C, Tsoumanis A, Rotsaert A, Vuylsteke B, Van den Bossche D, Paeleman E, De Baetselier I, Brosius I, Laumen J, Buyze J, Wouters K, Lynen L, Van Esbroeck M, Herssens N, Abdellati S, Declercq S, Reyniers T, Van Herrewege Y, Florence E, Kenyon C. Van Dijck C, et al. Lancet Infect Dis. 2021 May;21(5):657-667. doi: 10.1016/S1473-3099(20)30778-7. Epub 2021 Mar 4. Lancet Infect Dis. 2021. PMID: 33676596 Clinical Trial.

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Understanding Risk Factors for Oropharyngeal Gonorrhea Among Sex Workers Attending Sexual Health Clinics in 2 Australian Cities: Mixed Methods Study.
Phillips TR, Fairley CK, Maddaford K, McNulty A, Donovan B, Guy R, McIver R, Wigan R, Varma R, Ong JJ, Callander D, Skelsey G, Pony M, O'Hara D, Bilardi JE, Chow EP. Phillips TR, et al. JMIR Public Health Surveill. 2024 May 20;10:e46845. doi: 10.2196/46845. JMIR Public Health Surveill. 2024. PMID: 38767954 Free PMC article.

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Is it the end of mouthwash as an intervention for gonorrhoea?

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Is it the end of mouthwash as an intervention for gonorrhoea?

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