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. 2021 Aug:147:110525.
doi: 10.1016/j.jpsychores.2021.110525. Epub 2021 May 20.

Physical and mental health complications post-COVID-19: Scoping review

Sanaz Shanbehzadeh  1 , Mahnaz Tavahomi  2 , Nasibeh Zanjari  3 , Ismail Ebrahimi-Takamjani  4 , Somayeh Amiri-Arimi  5
Affiliations

Physical and mental health complications post-COVID-19: Scoping review

Sanaz Shanbehzadeh et al. J Psychosom Res. 2021 Aug.

Abstract

Objective: Several long-lasting health complications have been reported in previous coronavirus infections. Therefore, the aim of this study was to review studies that evaluated physical and mental health problems post-COVID-19.

Methods: Articles for inclusion in this scoping review were identified by searching the PubMed, Scopus, Web of Science and Google Scholar databases for items dated from 1 January to 7 November 2020. Observational studies evaluating physical health (musculoskeletal symptoms, functional status) or mental health status with a follow-up period longer than 1 month after discharge or after the onset of symptoms were included.

Results: This scoping review included 34 studies with follow-up periods of up to 3 months post-COVID-19. The most commonly reported physical health problems were fatigue (range 28% to 87%), pain (myalgia 4.5% to 36%), arthralgia (6.0% to 27%), reduced physical capacity (six-minute walking test range 180 to 561 m), and declines in physical role functioning, usual care and daily activities (reduced in 15% to 54% of patients). Common mental health problems were anxiety (range 6.5% to 63%), depression (4% to 31%) and post-traumatic stress disorder (12.1% to 46.9%). Greater fatigue, pain, anxiety and depression were reported in female patients and individuals admitted to intensive care. An overall lower quality of life was seen up to 3 months post-COVID-19.

Conclusions: This review highlights the presence of several physical and mental health problems up to 3 months post-COVID-19. The findings point to the need for comprehensive evaluation and rehabilitation post-COVID-19 to promote quality of life.

Keywords: Coronavirus; Follow up; Health; Post-discharge; Quality of life.

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Conflict of interest statement

The authors have no competing interests to report.

Figures

Fig. 1
Fig. 1
PRISMA flowchart for the literature review.
See this image and copyright information in PMC

References

    1. Woods J., Hutchinson N.T., Powers S.K., Roberts W.O., Gomez-Cabrera M.C., Radak Z., et al. The COVID-19 pandemic and physical activity. J. Sport Health Sci. 2020 doi: 10.1016/j.smhs.2020.05.006. - DOI - PMC - PubMed
    1. Team E.E. Note from the editors: World Health Organization declares novel coronavirus (2019-nCoV) sixth public health emergency of international concern. J. Eurosurveillance. 2020;25 doi: 10.2807/1560-7917.ES.2020.25.5.200131e. - DOI - PMC - PubMed
    1. Cipollaro L., Giordano L., Padulo J., Oliva F., Maffulli N. Musculoskeletal symptoms in SARS-CoV-2 (COVID-19) patients. J. Orthop. Surg. Res. 2020;15(1):178–184. - PMC - PubMed
    1. Wu Y., Xu X., Chen Z., Duan J., Hashimoto K., Yang L., et al. Nervous system involvement after infection with COVID-19 and other coronaviruses. J. Brain. Behav. 2020;87:18–22. https://doi:10.1001 - PMC - PubMed
    1. Ellul M.A., Benjamin L., Singh B., Lant S., Michael B.D., Easton A., et al. Neurological associations of COVID-19. Lancet Neurol. 2020 doi: 10.1016/S1474-4422(20)30221-0. - DOI - PMC - PubMed

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