Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Jul;17(3):337-343.
doi: 10.1016/j.hfc.2021.02.002.

Hypertension and Heart Failure with Preserved Ejection Fraction

Chan Joo Lee  1 , Sungha Park  2
Affiliations
Review

Hypertension and Heart Failure with Preserved Ejection Fraction

Chan Joo Lee et al. Heart Fail Clin. 2021 Jul.

Abstract

The prevalence of heart failure with preserved ejection fraction (HFpEF) is increasing rapidly, and its prognosis is as poor as that of HF with reduced EF. Hypertension is an important risk factor involved in the pathophysiology of HFpEF. Although treatment of hypertension lowers the incidence of HF and is beneficial in patients with HFpEF, there is conflicting evidence on this topic. This article discusses the pathophysiological mechanisms linking hypertension with HFpEF and also the current evidence on the treatment of hypertension in patients with HFpEF.

Keywords: Antihypertensive agents; Blood pressure; Heart failure; Hypertension.

PubMed Disclaimer

Conflict of interest statement

Disclosure The authors have nothing to declare. This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Ministry of Science and ICT (NRF-2020R1C1C1013627) and was also supported by Basic Science Research Program through the NRF funded by the Ministry of Education (NRF-2017R1D1A1B03034053).

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

LinkOut - more resources