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Review
. 2021 Jul;17(3):337-343.
doi: 10.1016/j.hfc.2021.02.002.

Hypertension and Heart Failure with Preserved Ejection Fraction

Chan Joo Lee  1 , Sungha Park  2
Affiliations
Review

Hypertension and Heart Failure with Preserved Ejection Fraction

Chan Joo Lee et al. Heart Fail Clin. 2021 Jul.

Abstract

The prevalence of heart failure with preserved ejection fraction (HFpEF) is increasing rapidly, and its prognosis is as poor as that of HF with reduced EF. Hypertension is an important risk factor involved in the pathophysiology of HFpEF. Although treatment of hypertension lowers the incidence of HF and is beneficial in patients with HFpEF, there is conflicting evidence on this topic. This article discusses the pathophysiological mechanisms linking hypertension with HFpEF and also the current evidence on the treatment of hypertension in patients with HFpEF.

Keywords: Antihypertensive agents; Blood pressure; Heart failure; Hypertension.

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Conflict of interest statement

Disclosure The authors have nothing to declare. This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Ministry of Science and ICT (NRF-2020R1C1C1013627) and was also supported by Basic Science Research Program through the NRF funded by the Ministry of Education (NRF-2017R1D1A1B03034053).

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