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Observational Study
. 2021 Aug;83(2):237-279.
doi: 10.1016/j.jinf.2021.05.023. Epub 2021 May 27.

One-year durability of anti-spike IgG to SARS-CoV-2: Preliminary data from the anticrown prospective observational study one year durability of COVID-19 anti-spike IgG

Amedeo F Capetti  1 , Fabio Borgonovo  2 , Davide Mileto  3 , Gloria Gagliardi  3 , Chiara Mariani  4 , Angelica Lupo  2 , Gianfranco Dedivitiis  2 , Paola Meraviglia  2 , Martina Pellicciotta  2 , Luciana Armiento  2 , Maria V Cossu  2 , Giuliano Rizzardini  2
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Observational Study

One-year durability of anti-spike IgG to SARS-CoV-2: Preliminary data from the anticrown prospective observational study one year durability of COVID-19 anti-spike IgG

Amedeo F Capetti et al. J Infect. 2021 Aug.

Abstract

Data are presented of 368/503 post-COVID-19 outpatients followed within the AntiCROWN Cohort who have a one-year control and a baseline assessment of anti-S1/S2 antibodies, detected with the The LIAISON® SARS-CoV-2 S1/S2 IgG solution by DiaSorin. Loss of response occurred in 4 subjects having a baseline level below 50 AU/mL.

Keywords: Antibodies; COVID-19; Coronavirus; Durability; Observational; Spike.

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Fig 1
Fig. 1
One Year follow-up of anti-S1/S2 antibody levels in subjects: A, with baselibe lavels <15 AU/mL; B, with baseline levels 15 to 50 AU/mL; C, with baseline levels >50 AU/mL. D: responses in vaccinated subjects (Results limited by ceiling cut-off effect at 400 AU/mL)).
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