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Case Reports
. 2021 Jul;268(7):2595-2596.
doi: 10.1007/s00415-021-10625-3. Epub 2021 May 30.

Acetyl-DL-leucine improves restless legs syndrome: a case report

Taylor Fields  1 , Benedikt Schoser  2 , Wolfgang Oertel  3 , Michael Strupp  4
Affiliations
Case Reports

Acetyl-DL-leucine improves restless legs syndrome: a case report

Taylor Fields et al. J Neurol. 2021 Jul.
No abstract available

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References

    1. Schoser B, Schautzer F, Bremova T, Strupp M (2019) Treatment of restless legs syndrome with acetyl-DL-leucine: accidental findings and a small case series. Eur J Neurol 26:348 - DOI
    1. Walters AS, LeBrocq C, Dhar A et al (2003) Validation of the International Restless Legs Syndrome Study Group rating scale for restless legs syndrome. Sleep Med 4:121–132 - DOI
    1. Kaya E, Smith DA, Smith C, Boland B, Strupp M, Platt FM (2020) Beneficial effects of acetyl-DL-leucine (ADLL) in a mouse model of Sandhoff disease. J Clin Med 8:9
    1. Hegdekar N, Lipinski MM, Sarkar C (2021) N-acetyl-L-leucine improves functional recovery and attenuates cortical cell death and neuroinflammation after traumatic brain injury in mice. Sci Rep 11:9249 - DOI
    1. Vibert N, Vidal PP (2001) In vitro effects of acetyl-DL-leucine (tanganil) on central vestibular neurons and vestibulo-ocular networks of the guinea-pig. Eur J Neurosci 13:735–748 - DOI

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