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Review
. 2022 Jan;36(1):12-19.
doi: 10.1177/02698811211008554. Epub 2021 May 29.

Psychedelics and health behaviour change

Affiliations
Review

Psychedelics and health behaviour change

Pedro J Teixeira et al. J Psychopharmacol. 2022 Jan.

Abstract

Healthful behaviours such as maintaining a balanced diet, being physically active and refraining from smoking have major impacts on the risk of developing cancer, diabetes, cardiovascular diseases and other serious conditions. The burden of the so-called 'lifestyle diseases'-in personal suffering, premature mortality and public health costs-is considerable. Consequently, interventions designed to promote healthy behaviours are increasingly being studied, e.g., using psychobiological models of behavioural regulation and change. In this article, we explore the notion that psychedelic substances such as psilocybin could be used to assist in promoting positive lifestyle change conducive to good overall health. Psilocybin has a low toxicity, is non-addictive and has been shown to predict favourable changes in patients with depression, anxiety and other conditions marked by rigid behavioural patterns, including substance (mis)use. While it is still early days for modern psychedelic science, research is advancing fast and results are promising. Here we describe psychedelics' proposed mechanisms of action and research findings pertinent to health behaviour change science, hoping to generate discussion and new research hypotheses linking the two areas. Therapeutic models including psychedelic experiences and common behaviour change methods (e.g., Cognitive Behaviour Therapy, Motivational Interviewing) are already being tested for addiction and eating disorders. We believe this research may soon be extended to help promote improved diet, exercise, nature exposure and also mindfulness or stress reduction practices, all of which can contribute to physical and psychological health and well-being.

Keywords: Psilocybin; interventions; public health; serotonin; therapy.

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Conflict of interest statement

Declaration of conflicting interests: PJT is the research director at The Synthesis Institute B.V.. MWJ is an advisor to AWAKN Life Sciences Inc., Beckley Psytech Ltd., Entheogen Biomedical Corp., Field Trip Psychedelics Inc., Mind Medicine Inc., Otsuka Pharmaceutical Development & Commercialization Inc., and Silo Pharma, Inc.; CT is an advisor for Entheon Biomedical Corp; RW is a member of the Clinical Advisory Board of the Usona Institute; and clinical director at The Synthesis Institute B.V.. DE is an advisor for Field Trip Psychedelics Inc. and Mydecine Innovations Group Inc. HD was funded by the Imperial College London President’s PhD Scholarships. RCH is a scientific advisor for Entheon Biomedical Corp., Mydecine Innovations Group Inc., The Synthesis Institute B.V., Usona Institute, Beckley Psychtech Ltd., Maya PBC, Osmind PBC, and TRYP Therapeutics Inc. HK declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

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