Neuroendocrine Tumors: Imaging Perspective

Rebecca K S Wong¹, Ur Metser², Patrick Veit-Haibach³

Affiliations

¹ Radiation Medicine Program, Princess Margaret Cancer Center, University Health Network, 610 University Ave, Toronto, ON M5G 2M9, Canada; Department of Radiation Oncology Temerty Faculty of Medicine, University of Toronto, 149 College Street, Suite 504, Toronto, ON M5T 1P5, Canada.
² Joint Department Medical Imaging, University Health Network, Mount Sinai Hospital & Women's College Hospital, University of Toronto, 610 University Ave, Suite 3-920, Toronto, ON M5G 2M9, Canada; Department of Medical Imaging, University of Toronto, 263 McCaul Street, 4th Floor, Toronto, ON M5T 1W7, Canada.
³ Joint Department Medical Imaging, University Health Network, Mount Sinai Hospital & Women's College Hospital, University of Toronto, 610 University Ave, Suite 3-920, Toronto, ON M5G 2M9, Canada; Department of Medical Imaging, University of Toronto, 263 McCaul Street, 4th Floor, Toronto, ON M5T 1W7, Canada. Electronic address: Patrick.Veit-Haibach@uhn.ca.

PMID: 34053579
DOI: 10.1016/j.cpet.2021.03.002

Review

Neuroendocrine Tumors: Imaging Perspective

Rebecca K S Wong et al. PET Clin. 2021 Jul.

. 2021 Jul;16(3):353-364.

doi: 10.1016/j.cpet.2021.03.002.

Authors

Rebecca K S Wong¹, Ur Metser², Patrick Veit-Haibach³

Affiliations

¹ Radiation Medicine Program, Princess Margaret Cancer Center, University Health Network, 610 University Ave, Toronto, ON M5G 2M9, Canada; Department of Radiation Oncology Temerty Faculty of Medicine, University of Toronto, 149 College Street, Suite 504, Toronto, ON M5T 1P5, Canada.
² Joint Department Medical Imaging, University Health Network, Mount Sinai Hospital & Women's College Hospital, University of Toronto, 610 University Ave, Suite 3-920, Toronto, ON M5G 2M9, Canada; Department of Medical Imaging, University of Toronto, 263 McCaul Street, 4th Floor, Toronto, ON M5T 1W7, Canada.
³ Joint Department Medical Imaging, University Health Network, Mount Sinai Hospital & Women's College Hospital, University of Toronto, 610 University Ave, Suite 3-920, Toronto, ON M5G 2M9, Canada; Department of Medical Imaging, University of Toronto, 263 McCaul Street, 4th Floor, Toronto, ON M5T 1W7, Canada. Electronic address: Patrick.Veit-Haibach@uhn.ca.

PMID: 34053579
DOI: 10.1016/j.cpet.2021.03.002

Abstract

This article summarizes the role of PET imaging for detection, characterization, and theranostic/therapy planning for neuroendocrine tumors. Topics in this article span overall imaging accuracy with mostly ⁶⁸Ga-DOTA-peptide imaging as well as basic principles of individualized dosimetry. There is also some discussion around further specialized approaches in dosimetry in theranostics. In addition, an overview of the literature on functional imaging in neuroendocrine tumors and the current understanding of imaging-derived clinical outcome prediction are presented.

Keywords: 68-Gallium DOTA-peptides; Dosimetry; Neuroendocrine tumors; Outcome prediction; PET imaging; Theranostic.

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Neuroendocrine Tumors: Imaging Perspective

Affiliations

Neuroendocrine Tumors: Imaging Perspective

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