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Review
. 2021 Jul;16(3):397-418.
doi: 10.1016/j.cpet.2021.03.005.

Theranostics in Brain Tumors

Affiliations
Review

Theranostics in Brain Tumors

Hossein Shooli et al. PET Clin. 2021 Jul.

Abstract

Theranostic nuclear oncology, mainly in neuro-oncology (neurotheranostics), aims to combine cancer imaging and therapy using the same targeting molecule. This approach tries to identify patients who are most likely to benefit from tumor molecular radionuclide therapy. The ability of radioneurotheranostic agents to interact with cancer cells at the molecular level with high specificity can significantly improve the effectiveness of cancer therapy. A variety of biologic targets are under investigation for treating brain tumors. PET-based precision imaging can substantially improve the therapeutic efficacy of radiotheranostic approach in brain tumors.

Keywords: Brain tumor; Neuro-oncology; Neurotheranostics; PET/CT; PET/MR imaging; Radioneurotheranostics; Theranostics.

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