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Review
. 2021 May 15:2021:5591573.
doi: 10.1155/2021/5591573. eCollection 2021.

A Systematic Review of Antiaging Effects of 23 Traditional Chinese Medicines

Lixin Wang  1 , Xu Zuo  2 , Zhuoer Ouyang  1 , Ping Qiao  1 , Fang Wang  2
Affiliations
Review

A Systematic Review of Antiaging Effects of 23 Traditional Chinese Medicines

Lixin Wang et al. Evid Based Complement Alternat Med. .

Abstract

Background: Aging is an inevitable stage of body development. At the same time, aging is a major cause of cancer, cardiovascular disease, and neurodegenerative diseases. Chinese herbal medicine is a natural substance that can effectively delay aging and is expected to be developed as antiaging drugs in the future. Aim of the review. This paper reviews the antiaging effects of 23 traditional Chinese herbal medicines or their active components. Materials and methods. We reviewed the literature published in the last five years on Chinese herbal medicines or their active ingredients and their antiaging role obtained through the following databases: PubMed, EMBASE, Scopus, and Web of Science.

Results: A total of 2485 papers were found, and 212 papers were screened after removing the duplicates and reading the titles. Twenty-three studies met the requirements of this review and were included. Among these studies, 13 articles used Caenorhabditis elegans as the animal model, and 10 articles used other animal models or cell lines.

Conclusion: Chinese herbal medicines or their active components play an antiaging role by regulating genes related to aging through a variety of signaling pathways. Chinese herbal medicines are expected to be developed as antiaging drugs or used in the medical cosmetology industry.

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Conflict of interest statement

The authors declare that they have no conflicts of interest.

Figures

Figure 1
Figure 1
A flowchart of literature search and selection in this review is described in detail.
Figure 2
Figure 2
Chemical structures of some of the main components of TCM.
Figure 3
Figure 3
Methodological quality of included in vivo studies.
Figure 4
Figure 4
The year of publication of the review article.
Figure 5
Figure 5
The country of publication of the review article.
See this image and copyright information in PMC

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