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Case Reports
. 2021 Jul:13:134-137.
doi: 10.1016/j.jdcr.2021.05.010. Epub 2021 May 26.

A case of severe cutaneous adverse reaction following administration of the Janssen Ad26.COV2.S COVID-19 vaccine

Kristen Lospinoso  1   2 , Cameron S Nichols  1 , Stephen J Malachowski  1 , Mark C Mochel  1   3 , Fnu Nutan  1
Affiliations
Case Reports

A case of severe cutaneous adverse reaction following administration of the Janssen Ad26.COV2.S COVID-19 vaccine

Kristen Lospinoso et al. JAAD Case Rep. 2021 Jul.
No abstract available

Keywords: AGEP; AGEP, acute generalized exanthematous pustulosis; COVID-19; DRESS; DRESS, drug reaction with eosinophilia and systemic symptoms; SCAR, severe cutaneous adverse reaction; severe adverse cutaneous reaction; vaccine.

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Conflict of interest statement

None declared.

Figures

Fig 1
Fig 1
Widespread, erythematous plaques (A and B) with small, non-follicular pustules and scale (C).
Fig 2
Fig 2
Histopathology of a biopsy from the right shoulder with (A) epidermal spongiosis and dermal neutrophilic inflammation with occasional eosinophils (hematoxylin-eosin staining; original magnification, ×200) and (B) scattered subcorneal neutrophilic pustules. (Hematoxylin-eosin staining; original magnification, ×400.)
Fig 3
Fig 3
Markedly reduced density and decreased intensity of erythematous plaques on the torso and extremities (A and B) compared with the initial presentation (Fig 1). Improving lower extremity edema was also seen (B) but not pictured in Fig 1.
See this image and copyright information in PMC

Comment in

References

    1. Livingston E.H., Malani P.N., Creech C.B. The Johnson & Johnson vaccine for COVID-19. JAMA. 2021;325(15):1575. - PubMed
    1. Wadman M. Public needs to prep for vaccine side effects. Science. 2020;370(6520):1022. - PubMed
    1. Wei N., Fishman M., Wattenberg D., Gordon M., Lebwohl M. ‘COVID arm’: a reaction to the Moderna vaccine. JAAD Case Rep. 2021;10:92–95. - PMC - PubMed
    1. Jedlowski P.M., Jedlowski M.F. Morbilliform rash after administration of Pfizer-BioNTech COVID-19 mRNA vaccine. Dermatol Online J. 2021;27(1) 13030/qt4xs486zg. - PubMed
    1. Duong T.A., Valeyrie-Allanore L., Wolkenstein P., Chosidow O. Severe cutaneous adverse reactions to drugs. Lancet. 2017;390(10106):1996–2011. - PubMed

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