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Review
. 2021 Mar 9;1(1):ltab004.
doi: 10.1093/immadv/ltab004. eCollection 2021 Jan.

An overview of CAR T-cell clinical trial activity to 2021

Antonella Adami  1 , John Maher  1   2   3   4
Affiliations
Review

An overview of CAR T-cell clinical trial activity to 2021

Antonella Adami et al. Immunother Adv. .

Abstract

Immunotherapy of cancer using chimeric antigen receptor-engineered T-cells has transformed the management of selected haematological malignancies, triggering intense clinical trial activity in this arena. This article summarises trial activity that has been published to date across the spectrum of haematological and solid tumour types.

Keywords: CAR T-cell; cancer; clinical trials; immunotherapy.

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