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. 2021 Dec;88(12):1187-1194.
doi: 10.1007/s12098-021-03776-8. Epub 2021 May 31.

Profile and Epidemiology of Intussusception in Children Under-Two Years of Age: A Prospective Surveillance

Manoja Kumar Das  1 , Narendra Kumar Arora  2 , John Mathai  3 , Cenita J Sam  4 , Rajamani G  5 , Krishnaswamy R  6 , Jothilakshmi K  7 , Pavai Arunachalam  4 , Bini Gupta  2
Affiliations

Profile and Epidemiology of Intussusception in Children Under-Two Years of Age: A Prospective Surveillance

Manoja Kumar Das et al. Indian J Pediatr. 2021 Dec.

Abstract

Objective: To report background intussusception epidemiology in children under-two years in Coimbatore district of Tamil Nadu state, India, prior to rotavirus vaccine (RVV) introduction.

Methods: Prospective sentinel surveillance was done at four hospitals in Coimbatore during April 2016 to September 2017. The children aged >1 mo and < 24 mo with diagnosed intussusception were recruited and data on clinical, treatment, diet, immunization, and sociodemography were collected.

Results: Sixty-eight children with intussusception were recruited. Among them 76.5% were infants with male predominance (57.4%) and 48.5% were 4-8 mo old. Vomiting (83.8%), pain in abdomen (including excessive crying) (72.1%), and bloody stools (45.6%) were the main symptoms. Reduction was tried in 92.6% cases with success in 83.8%. Surgery was needed by 16.2% children. No child died. Any RVV dose was received by 24.1% children and 2 children received RVV in 8-21 d and none within 1-7 d window. The incidence of intussusception requiring hospitalization was estimated to be 36.4 and 11.7 cases/100,000 children/y for the first and second years, respectively.

Conclusion: Intussusception occurred in infants even without RVV exposure. Continued surveillance is needed to document the changes in intussusception epidemiology after RVV introduction.

Keywords: Children; Coimbatore; Incidence; Intussusception; Prospective surveillance; South India.

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