HbA2 induction: the merit of pancellularity in sickle cell disease
- PMID: 34060070
- DOI: 10.1111/bjh.17562
HbA2 induction: the merit of pancellularity in sickle cell disease
Comment on
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Delta-globin gene expression improves sickle cell disease in a humanised mouse model.Br J Haematol. 2021 Jun;193(6):1228-1237. doi: 10.1111/bjh.17561. Epub 2021 May 28. Br J Haematol. 2021. PMID: 34046885
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- Steinberg MH, Nagel RL. Hemoglobins of the embryo and fetus and minor hemoglobins of adults. In: MH Steinberg, BG Forget, DR Higgs, RL Nagel, editors. Disorders of Hemoglobin: Genetics, Pathophysiology and Clinical Management. Cambridge: Cambridge University Press, 2001; p. 1268. Chp 10:197-230.
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- Inagaki K, Inagaki J, Dumoulin A, Padovan JC, Chait BT, Popowicz A, et al. Expression and properties of recombinant HbA2 (alpha2delta2) and hybrids containing delta-beta sequences. J Protein Chem. 2000;19:649-62.
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- Donze D, Jeancake PH, Townes TM. Activation of delta-globin gene expression by erythroid Krupple-like factor: a potential approach for gene therapy of sickle cell disease. Blood. 1996;88:4051-7.
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