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Review
. 2021 May 5;26(9):2709.
doi: 10.3390/molecules26092709.

The Anti-Leukemic Activity of Natural Compounds

Coralia Cotoraci  1 , Alina Ciceu  2 , Alciona Sasu  1 , Eftimie Miutescu  3 , Anca Hermenean  2   4
Affiliations
Review

The Anti-Leukemic Activity of Natural Compounds

Coralia Cotoraci et al. Molecules. .

Abstract

The use of biologically active compounds has become a realistic option for the treatment of malignant tumors due to their cost-effectiveness and safety. In this review, we aimed to highlight the main natural biocompounds that target leukemic cells, assessed by in vitro and in vivo experiments or clinical studies, in order to explore their therapeutic potential in the treatment of leukemia: acute myeloid leukemia (AML), chronic myeloid leukemia (CML), acute lymphocytic leukemia (ALL), and chronic lymphocytic leukemia (CLL). It provides a basis for researchers and hematologists in improving basic and clinical research on the development of new alternative therapies in the fight against leukemia, a harmful hematological cancer and the leading cause of death among patients.

Keywords: anti-leukemic; antioxidants; flavonoids; lymphoblastic leukemia; myeloid leukemia.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Natural compounds against acute myeloid leukemia (AML).
Figure 2
Figure 2
Natural compounds against chronic myeloid leukemia (CML).
Figure 3
Figure 3
Natural compounds against acute lymphoblastic leukemia (ALL).
Figure 4
Figure 4
Natural compounds against chronic lymphocytic leukemia (CLL).
See this image and copyright information in PMC

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