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. 2021 May 15;13(5):918.
doi: 10.3390/v13050918.

Taxonomy of Phleboviruses, Emphasizing Those That Are Sandfly-Borne

Charles H Calisher  1 , Mattia Calzolari  2
Affiliations

Taxonomy of Phleboviruses, Emphasizing Those That Are Sandfly-Borne

Charles H Calisher et al. Viruses. .

Abstract

Sandfly-borne phleboviruses (phylum Negarnavaricota, realm Riboviria, kingdom Orthornavirae, genus Phlebovirus) comprise three genome segments of ribonucleic acid (RNA) and which encode an RNA-dependent RNA polymerase, which they use to transcribe the viral RNA genome into messenger RNA and to replicate the genome. At least some of these viruses cause mild 3-day fevers in humans but some also have been associated with more severe illnesses in humans. The 67 recognized phleboviruses are listed here in a table composed by the authors from International Committee on Taxonomy of Viruses reports as well as the scientific literature.

Keywords: Phlebovirus; reassortant virus; sand fly; virus species.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Midpoint rooted maximum likelihood tree obtained with amino acid sequences of the RdRp of available phleboviruses. Sequences in red: ascribable to the same species according the 95% identity threshold. Bootstrap values >85% are shown over the branch.
See this image and copyright information in PMC

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