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Review
. 2021 May 21;14(11):2715.
doi: 10.3390/ma14112715.

Can Ultrasound Therapy Be an Environmental-Friendly Alternative to Non-Steroidal Anti-Inflammatory Drugs in Knee Osteoarthritis Treatment?

Rodica Ana Ungur  1 , Viorela Mihaela Ciortea  1 , Laszlo Irsay  1 , Alina Deniza Ciubean  1 , Bogdana Adriana Năsui  2 , Răzvan Andrei Codea  3 , Victoria Emilia Singurean  1 , Oana Bianca Groza  1 , Simona Căinap  4 , Georgiana Smaranda Martiș Petruț  5 , Cristin Borda  3 , Ileana Monica Borda  1
Affiliations
Review

Can Ultrasound Therapy Be an Environmental-Friendly Alternative to Non-Steroidal Anti-Inflammatory Drugs in Knee Osteoarthritis Treatment?

Rodica Ana Ungur et al. Materials (Basel). .

Abstract

The non-steroidal anti-inflammatory drugs (NSAIDs) are the most used drugs in knee OA (osteoarthritis) treatment. Despite their efficiency in pain and inflammation alleviation, NSAIDs accumulate in the environment as chemical pollutants and have numerous genetic, morphologic, and functional negative effects on plants and animals. Ultrasound (US) therapy can improve pain, inflammation, and function in knee OA, without impact on environment, and with supplementary metabolic beneficial effects on cartilage compared to NSAIDs. These features recommend US therapy as alternative for NSAIDs use in knee OA treatment.

Keywords: environment pollutants; health benefits; non-steroidal anti-inflammatory drugs; ultrasound therapy.

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Conflict of interest statement

The authors declare no conflict of interest.

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