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Review
. 2021 May 6;9(5):521.
doi: 10.3390/biomedicines9050521.

Carotid Atherosclerosis, Ultrasound and Lipoproteins

Arcangelo Iannuzzi  1 , Paolo Rubba  2 , Marco Gentile  2 , Vania Mallardo  2 , Ilenia Calcaterra  2 , Alessandro Bresciani  1 , Giuseppe Covetti  1 , Gianluigi Cuomo  3 , Pasquale Merone  3 , Anna Di Lorenzo  3 , Roberta Alfieri  3 , Emilio Aliberti  4 , Francesco Giallauria  3 , Matteo Nicola Dario Di Minno  2 , Gabriella Iannuzzo  2
Affiliations
Review

Carotid Atherosclerosis, Ultrasound and Lipoproteins

Arcangelo Iannuzzi et al. Biomedicines. .

Abstract

Carotid artery plaques are considered a measure of atherosclerosis and are associated with an increased risk of atherosclerotic cardiovascular disease, particularly ischemic strokes. Monitoring of patients with an elevated risk of stroke is critical in developing better prevention strategies. Non-invasive imaging allows us to directly see atherosclerosis in vessels and many features that are related to plaque vulnerability. A large body of evidence has demonstrated a strong correlation between some lipid parameters and carotid atherosclerosis. In this article, we review the relationship between lipids and atherosclerosis with a focus on carotid ultrasound, the most common method to estimate atherosclerotic load.

Keywords: atherosclerosis; carotid ultrasound; lipids.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Increased IMT of the common carotid artery (1.4 mm far wall; 1.6 mm near wall). Legend: CC, common carotid; Bulb, carotid bulb; ICA, internal carotid artery; JUG, jugular vein.
See this image and copyright information in PMC

References

    1. Rothwell P.M. Incidence, risk factors and prognosis of stroke and TIA: The need for high-quality, large-scale epidemiological studies and metaanalyses. Cerebrovasc. Dis. 2003;16:2–10. doi: 10.1159/000070271. - DOI - PubMed
    1. Ooi Y.C., Gonzalez N.R. Management of extracranial carotid artery disease. Cardiol. Clin. 2015;33:1–35. doi: 10.1016/j.ccl.2014.09.001. - DOI - PMC - PubMed
    1. Pauciullo P., Iannuzzi A., Sartorio R., Irace C., Covetti G., Di Costanzo A., Rubba P. Increased intima-media thickness of the common carotid artery in hypercholesterolemic children. Arterioscler. Thromb. 1994;14:1075–1079. doi: 10.1161/01.ATV.14.7.1075. - DOI - PubMed
    1. Tonstad S., Joakimsen O., Stenland-Bugge E., Leren T.P., Ose L., Rusell D., Bonaa K.H. Risk factors related to carotid intima-media thickness and plaque in children with familial hypercholesterolemia and control subjects. Arterioscler. Thromb. Vasc. Biol. 1996;16:984–991. doi: 10.1161/01.ATV.16.8.984. - DOI - PubMed
    1. Raal F.J., Hovingh G.K., Catapano A.L. Familial hypercholesterolemia treatments: Guidelines and new therapies. Atherosclerosis. 2018;277:483–492. doi: 10.1016/j.atherosclerosis.2018.06.859. - DOI - PubMed

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