Editorial

. 2021 May 17;10(5):790.

doi: 10.3390/antiox10050790.

Oxidative Stress and Inflammation in Retinal Degeneration

Ravirajsinh N Jadeja¹, Pamela M Martin^{1

2

3}

Affiliations

¹ Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
² Department of Ophthalmology, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
³ James and Jean Culver Vision Discovery Institute, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.

PMID: 34067655
PMCID: PMC8156590
DOI: 10.3390/antiox10050790

Editorial

Oxidative Stress and Inflammation in Retinal Degeneration

Ravirajsinh N Jadeja et al. Antioxidants (Basel). 2021.

. 2021 May 17;10(5):790.

doi: 10.3390/antiox10050790.

Authors

Ravirajsinh N Jadeja¹, Pamela M Martin^{1

2

3}

Affiliations

¹ Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
² Department of Ophthalmology, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
³ James and Jean Culver Vision Discovery Institute, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.

PMID: 34067655
PMCID: PMC8156590
DOI: 10.3390/antiox10050790

Abstract

Inflammation and oxidative stress play prominent roles in the pathogenesis of many degenerative diseases of the retina, such as age-related macular degeneration (AMD), diabetic retinopathy (DR), retinal vein occlusion, and retinitis pigmentosa [...].

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Conflict of interest statement

The authors declare no conflict of interest.

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References

1. Nishimura Y., Hara H., Kondo M., Hong S., Matsugi T. Oxidative Stress in Retinal Diseases. Oxidative Med. Cell. Longev. 2017;2017:4076518. doi: 10.1155/2017/4076518. - DOI - PMC - PubMed
1. E B.D., Marfany G. The Relevance of Oxidative Stress in the Pathogenesis and Therapy of Retinal Dystrophies. Antioxidants. 2020;9:347. doi: 10.3390/antiox9040347. - DOI - PMC - PubMed
1. Whitcup S.M., Nussenblatt R.B., Lightman S.L., Hollander D.A. Inflammation in retinal disease. Int. J. Inflam. 2013;2013:724648. doi: 10.1155/2013/724648. - DOI - PMC - PubMed
1. Nita M., Grzybowski A. The Role of the Reactive Oxygen Species and Oxidative Stress in the Pathomechanism of the Age-Related Ocular Diseases and Other Pathologies of the Anterior and Posterior Eye Segments in Adults. Oxid. Med. Cell. Longev. 2016;2016:3164734. doi: 10.1155/2016/3164734. - DOI - PMC - PubMed
1. Hogan M.J. Role of the retinal pigment epithelium in macular disease. Trans. Am. Acad Ophthalmol. Otolaryngol. 1972;76:64–80. - PubMed

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Oxidative Stress and Inflammation in Retinal Degeneration

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Oxidative Stress and Inflammation in Retinal Degeneration

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