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Review
. 2021 May 13;11(5):1384.
doi: 10.3390/ani11051384.

Research Progress on Oxidative Stress and Its Nutritional Regulation Strategies in Pigs

Yue Hao  1 , Mingjie Xing  1 , Xianhong Gu  1
Affiliations
Review

Research Progress on Oxidative Stress and Its Nutritional Regulation Strategies in Pigs

Yue Hao et al. Animals (Basel). .

Abstract

Oxidative stress refers to the dramatic increase in the production of free radicals in human and animal bodies or the decrease in the ability to scavenging free radicals, thus breaking the antioxidation-oxidation balance. Various factors can induce oxidative stress in pig production. Oxidative stress has an important effect on pig performance and healthy growth, and has become one of the important factors restricting pig production. Based on the overview of the generation of oxidative stress, its effects on pigs, and signal transduction pathways, this paper discussed the nutritional measures to alleviate oxidative stress in pigs, in order to provide ideas for the nutritional research of anti-oxidative stress in pigs.

Keywords: nutritional additive modulation; oxidative stress; performance; pigs; signaling pathways.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
When the oxidative system in the body is stronger than the antioxidant system, the generation of excess ROS cannot be scavenged in time. This disrupts the homeostasis of redox balance in the body and causes oxidative stress, ultimately leading to DNA, membrane, protein, and lipid damage.
Figure 2
Figure 2
The structural regions of Nrf2 and Keap1 proteins. A, Domains of Nrf2; B, Domains of Keap1.
Figure 3
Figure 3
Signaling pathway of Keap1/Nrf2/ARE under oxidative stress.
Figure 4
Figure 4
Signaling pathway of MAPK under oxidative stress.
See this image and copyright information in PMC

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