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Review
. 2021 May 29;8(6):456.
doi: 10.3390/children8060456.

Molecular Genetics in Neuroblastoma Prognosis

Margherita Lerone  1 , Marzia Ognibene  1 , Annalisa Pezzolo  2 , Giuseppe Martucciello  3   4 , Federico Zara  1   4 , Martina Morini  5 , Katia Mazzocco  6
Affiliations
Review

Molecular Genetics in Neuroblastoma Prognosis

Margherita Lerone et al. Children (Basel). .

Abstract

In recent years, much research has been carried out to identify the biological and genetic characteristics of the neuroblastoma (NB) tumor in order to precisely define the prognostic subgroups for improving treatment stratification. This review will describe the major genetic features and the recent scientific advances, focusing on their impact on diagnosis, prognosis, and therapeutic solutions in NB clinical management.

Keywords: TRK; exosomes; genetics; hypoxia; liquid biopsy; neuroblastoma; telomere maintenance.

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Conflict of interest statement

The authors declare no conflict of interest.

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