Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 2021 Jun 1;26(1):50.
doi: 10.1186/s40001-021-00520-y.

Prognostic factors affecting the short-term efficacy of non-surgical treatment of chronic periodontitis: a multilevel modeling analysis

Hui-Jie Liu #  1   2 , Bo Wang #  1 , Ao-Chen Wang  3 , Dan-Hong Zhang  1   2 , Cui Mao  1   2 , Qiu-Hong Li  4
Affiliations
Comparative Study

Prognostic factors affecting the short-term efficacy of non-surgical treatment of chronic periodontitis: a multilevel modeling analysis

Hui-Jie Liu et al. Eur J Med Res. .

Abstract

Background: This study is aimed to analyze the prognostic factors affecting the short-term efficacy of non-surgical treatment of patients in periodontitis from stage II to stage IV by the multilevel modeling analysis.

Materials and methods: A total of 58 patients with chronic periodontitis were included in this study. Patients were clinically explored before and 3 months after the treatment and the difference in probing depth was determined [Reduction of probing depth (Δ PD) = baseline PD - finial probing depth (FPD)] which is considered as the therapeutic evaluation. Three different levels were analyzed: patients, teeth and sites to construct a multi-layer linear model.

Results: Probing depth (PD) improved significantly compared with that before treatment (p < 0.05), in which FPD was (3.90 ± 1.39) mm, and the ΔPD was (1.79 ± 0.97) mm. Compared with the mesial sites and distal sites of the multi-rooted teeth, the number of PD ≥ 5 mm or PD < 5 mm after the treatment was significantly different (P < 0.05), and the proportion of PD < 5 mm was higher in mesial sites. The null model showed that Δ PD varied greatly between groups at various levels (P < 0.001), with prediction variable of site level, tooth level, and patient level accounted for 66%, 18%, and 16% of the overall difference, respectively. The complete model showed that the Δ PD of smokers was significantly lower than that of non-smokers (P < 0.001). The Δ PD of the mesial and distal sites was larger than that of the buccolingual central site (P < 0.001). The Δ PD of single-rooted teeth was larger than that of multi-rooted teeth (P < 0.001). The baseline PD, tooth mobility (TM), bleeding index (BI), clinical attachment loss (CAL) were significantly negatively correlated with Δ PD (P < 0.001).

Conclusions: Patients with periodontitis from stage II to stage IV, who were non-smoking, have good compliance, good awareness of oral health, and low percentage sites with PD ≥ 5 mm at baseline, single-rooted teeth with hypomobility, less clinical attachment loss and lower bleeding index and sites of mesial or distal can obtain an ideal short-term efficacy of non-surgical treatment.

Keywords: Multilevel linear model; Non-surgical treatment; Periodontitis; Prognosis.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
The inclusion flowchart of patients in this study
Fig. 2
Fig. 2
Proportion of PD before and after non-surgical treatment
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Tanner ACR. Anaerobic culture to detect periodontal and caries pathogens. J Oral Biosci. 2015;57:18–26. doi: 10.1016/j.job.2014.08.001. - DOI - PMC - PubMed
    1. Chandki R, Banthia P, Banthia R. Biofilms: a microbial home. J Indian Soc Periodontol. 2011;15:111–114. doi: 10.4103/0972-124X.84377. - DOI - PMC - PubMed
    1. Tonetti MS, Greenwell H, Kornman KS. Staging and grading of periodontitis: Framework and proposal of a new classification and case definition. J Periodontol. 2018;89(Suppl 1):S159–S172. doi: 10.1002/JPER.18-0006. - DOI - PubMed
    1. Badersten A, Nilvéus R, Egelberg J. Effect of nonsurgical periodontal therapy I Moderately advanced periodontitis. J Clin Periodontol. 1981;8:57–72. doi: 10.1111/j.1600-051X.1981.tb02024.x. - DOI - PubMed
    1. Drisko CL. Periodontal debridement: still the treatment of choice. J Evid Based Dent Pract. 2014;14(Suppl):33–41.e1. doi: 10.1016/j.jebdp.2014.02.007. - DOI - PubMed

LinkOut - more resources