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. 2021 Aug 1;63(8):e480-e489.
doi: 10.1097/JOM.0000000000002252.

A Health Surveillance Study of Workers Employed at a Copper Smelter-Effects of Long-Term Exposure to Copper on Lung Function Using Spirometric Data

Lisa-Marie Haase  1 , Thomas Birk, Annette M Bachand, Kenneth A Mundt
Affiliations

A Health Surveillance Study of Workers Employed at a Copper Smelter-Effects of Long-Term Exposure to Copper on Lung Function Using Spirometric Data

Lisa-Marie Haase et al. J Occup Environ Med. .

Abstract

Objective: Significantly lower permissible occupational exposure limits for copper dust are being discussed in Europe and other jurisdictions. However, little data are published on exposures in occupational settings and copper-specific effects in humans. Hence, a health surveillance study was performed among workers employed at a copper smelter between 1972 and 2018.

Methods: Possible effects of long-term exposures to dust containing copper on lung function were assessed. Specifically, declines in forced expiratory volume in 1 second (FEV1) were compared between a copper-exposed and control group. Cumulative copper exposures were derived from historical airborne monitoring data.

Results: FEV1 declines among exposed and control never smokers were similar to a typical age-dependent decline of 29 mL/y.

Conclusion: The study findings indicate that cumulative inhalable copper dust exposure averaging 4.61 mg/m3-years over an exposure duration of ∼22 years is not associated with adverse effects on lung function.

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