Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Jun 1;4(6):e2110700.
doi: 10.1001/jamanetworkopen.2021.10700.

Reporting of Sociodemographic Variables in Randomized Clinical Trials, 2014-2020

Aaron M Orkin  1   2 , Gina Nicoll  3   4 , Navindra Persaud  1   2   5 , Andrew D Pinto  1   4   5
Affiliations

Reporting of Sociodemographic Variables in Randomized Clinical Trials, 2014-2020

Aaron M Orkin et al. JAMA Netw Open. .

Abstract

This cross-sectional study assesses the frequency and thoroughness of reporting of sociodemographic variables in randomized clinical trials published in 5 high-impact health journals from January 2014 to July 2020.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest Disclosures: Dr Orkin reported being supported by the Canadian Institutes of Health Research Postdoctoral Fellowship Program and the Department of Family and Community Medicine, Faculty of Medicine, University of Toronto. Dr Persaud reported receiving grants from the Canada Research Chairs Program and the Canadian Institutes of Health Research outside the submitted work. Dr Pinto reported being supported as a clinician-scientist by the Department of Family and Community Medicine, Faculty of Medicine, University of Toronto; the Department of Family and Community Medicine, St Michael’s Hospital; the Li Ka Shing Knowledge Institute, and St Michael’s Hospital; by a fellowship from the Physicians’ Services Incorporated Foundation; and as the associate director for clinical research at the University of Toronto Practice-Based Research Network. Dr Pinto reported receiving honoraria for presentations at Queen’s University (2010), the University of Saskatchewan (2012), Mount Sinai Hospital (2012), the Toronto Reference Library (2016), the Law Society of Ontario (2016), the Japan Network of Health Promoting Hospitals and Health Services (2018), the Joint Centre for Bioethics, University of Toronto (2019), McMaster University (2020), and Ghent University, Belgium (2020). Dr Pinto also reported serving as an unpaid scientific advisor to a start-up company, Mutuo Health Solutions. No other disclosures were reported.

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Marmot M. Social determinants of health inequalities. Lancet. 2005;365(9464):1099-1104. doi:10.1016/S0140-6736(05)71146-6 - DOI - PubMed
    1. Van Spall HGC, Toren A, Kiss A, Fowler RA. Eligibility criteria of randomized controlled trials published in high-impact general medical journals: a systematic sampling review. JAMA. 2007;297(11):1233-1240. doi:10.1001/jama.297.11.1233 - DOI - PubMed
    1. Wilder J, Saraswathula A, Hasselblad V, Muir A. A systematic review of race and ethnicity in hepatitis C clinical trial enrollment. J Natl Med Assoc. 2016;108(1):24-29. doi:10.1016/j.jnma.2015.12.004 - DOI - PMC - PubMed
    1. Ramasubbu K, Gurm H, Litaker D. Gender bias in clinical trials: do double standards still apply? J Womens Health Gend Based Med. 2001;10(8):757-764. doi:10.1089/15246090152636514 - DOI - PubMed
    1. Robinson L, Adair P, Coffey M, Harris R, Burnside G. Identifying the participant characteristics that predict recruitment and retention of participants to randomised controlled trials involving children: a systematic review. Trials. 2016;17(1):294. doi:10.1186/s13063-016-1415-0 - DOI - PMC - PubMed