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. 2021 May;26(3):1-4.

Bimekizumab for Moderate-to-Severe Plaque Psoriasis

Ryan D Gotesman  1 , Ron Vender  2
Affiliations
  • PMID: 34077151
Free article

Bimekizumab for Moderate-to-Severe Plaque Psoriasis

Ryan D Gotesman et al. Skin Therapy Lett. 2021 May.
Free article

Abstract

Psoriasis is an immune-mediated inflammatory skin disease that affects about 2% of the population and is associated with many comorbidities. Recent advances have demonstrated interleukin (IL)-17 signaling plays a crucial role in the pathogenesis of psoriasis. Bimekizumab is a novel monoclonal antibody treatment for psoriasis that uses a single binding site to inhibit IL-17A and IL-17F. Here we will discuss the safety and efficacy of bimekizumab in the treatment of moderate-to-severe plaque psoriasis.

Keywords: IL-17; bimekizumab; interleukin-17A; interleukin-17F; plaque psoriasis.

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Conflict of interest statement

Ryan Gotesman has no conflicts of interest to disclose. Ron Vender has been a consultant, and/or scientific advisor, and/or investigator, and/or speaker for Amgen, AbbVie, Astellas, Bausch Health/Valeant, BMS, Boehringer Ingelheim, Celgene, Dermira, Eli Lilly, Galderma, GSK, Janssen, Leo Pharma, Merck (MSD), Merck Serono, Novartis, Pfizer, Regeneron, Roche, Sanofi-Aventis/Genzyme, Sun Pharma, Takeda and UCB.

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