Creatine promotes metastatic dissemination
- PMID: 34077711
- DOI: 10.1016/j.cmet.2021.05.012
Creatine promotes metastatic dissemination
Abstract
The molecular regulation of cancer metastasis is not fully understood. In this issue of Cell Metabolism, Zhang et al. (2021) discover that creatine promotes cancer metastasis in mice by promoting activation of the MPS1-Smad2/3 axis.
Crown Copyright © 2021. Published by Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests The authors declare no competing interests.
Comment on
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Creatine promotes cancer metastasis through activation of Smad2/3.Cell Metab. 2021 Jun 1;33(6):1111-1123.e4. doi: 10.1016/j.cmet.2021.03.009. Epub 2021 Apr 2. Cell Metab. 2021. PMID: 33811821
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