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Comment
. 2021 Jun 1;33(6):1071-1072.
doi: 10.1016/j.cmet.2021.05.010.

Can tumor cells take it all away?

Anna Kohl  1 , Kung-Chi Kao  1 , Ping-Chih Ho  2
Affiliations
Free article
Comment

Can tumor cells take it all away?

Anna Kohl et al. Cell Metab. .
Free article

Abstract

Tumor cells utilize glucose to engage in aerobic glycolysis, fulfilling their metabolic demands for extensive proliferation. A recent study in Nature discovers that tumor-infiltrating myeloid cells exhibit a superior glucose uptake capacity over tumor cells, which present enhanced glutamine metabolism, suggesting that nutrient partitioning in the TME might be more complex than previously thought.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

Comment on

  • Cell-programmed nutrient partitioning in the tumour microenvironment.
    Reinfeld BI, Madden MZ, Wolf MM, Chytil A, Bader JE, Patterson AR, Sugiura A, Cohen AS, Ali A, Do BT, Muir A, Lewis CA, Hongo RA, Young KL, Brown RE, Todd VM, Huffstater T, Abraham A, O'Neil RT, Wilson MH, Xin F, Tantawy MN, Merryman WD, Johnson RW, Williams CS, Mason EF, Mason FM, Beckermann KE, Vander Heiden MG, Manning HC, Rathmell JC, Rathmell WK. Reinfeld BI, et al. Nature. 2021 May;593(7858):282-288. doi: 10.1038/s41586-021-03442-1. Epub 2021 Apr 7. Nature. 2021. PMID: 33828302 Free PMC article.

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