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Randomized Controlled Trial
. 2021 Jun 2;21(1):286.
doi: 10.1186/s12888-021-03280-5.

Effect of Hope-oriented group counseling on mental health of infertile women with failed IVF cycles: a randomized controlled trial

Roya Rahimi  1 , Shirin Hasanpour  2 , Mojgan Mirghafourvand  3 , Khalil Esmaeilpour  4
Affiliations
Randomized Controlled Trial

Effect of Hope-oriented group counseling on mental health of infertile women with failed IVF cycles: a randomized controlled trial

Roya Rahimi et al. BMC Psychiatry. .

Abstract

Background: Considering the prevalence of infertility in the community and the consequences of failure of infertility treatments on women's mental health, interventions that can control stress, anxiety and depression in infertile women with a history of IVF failure will be very helpful. This study aimed to determine the effects of hope-oriented group counseling on mental health (primary outcome) and quality of life (QoL) (secondary outcome) of women with failed IVF cycles.

Method: This randomized controlled trial was conducted on 60 women with failed IVF cycles visiting Infertility Clinic at Al-Zahra Teaching Hospital of Tabriz- Iran. Participants were allocated to the intervention group (n = 30) and control group (n = 30) based on a randomized block design. Hope-oriented group counseling was provided to the intervention group in six 45-60 min sessions (once a week). The control group only received routine care to undergo another IVF cycle. The Depression Anxiety Stress Scale-21 (DASS-21) and the SF-12 Quality of Life Scale were filled out by interviewing the participants before the intervention and one week and one month after the intervention. After intervention 26 participants in each group were included in the analysis.

Results: There was no significant difference between the intervention and control groups in the socio-demographic profile of participants (P > 0.05). The post-intervention mean score of stress (adjusted mean difference = - 1.7, 95% confidence interval: - 3.2 to - 0.3, P = 0.018) and depression (adjusted mean difference = - 1.3, 95% confidence interval: - 4.7 to - 1.5, P < 0.001) was significantly lower in the intervention group compared to the control. Although the mean anxiety score was lower in the intervention group compared to the control, the difference between them was not statistically significant (adjusted mean difference = - 1.1, 95% confidence interval: - 2.6 to 0.4, P = 0.153). The mean score of QoL was significantly higher in the intervention group than that of the control group (adjusted mean difference = 6.9, 95% confidence interval: 5.1 to 8.8, P < 0.001).

Conclusion: Hope-oriented group counseling was effective in reducing stress and depression and improving QoL in women with failed IVF cycles. It is recommended to use this counseling approach, along with other methods, to improve the mental health of women with failed IVF cycles.

Trial registration: TCT Registration Number: TCTR 20191017003 , registered on October 17, 2019.

Keywords: Counseling; Hope therapy; IVF; Infertility; Mental health.

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Conflict of interest statement

The authors have no competing interests.

Figures

Fig. 1
Fig. 1
Flow Diagram
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References

    1. Dehghani Firouzabadi R, Janati S, Razi MH. The effect of intrauterine human chorionic gonadotropin injection before embryo transfer on the implantation and pregnancy rate in infertile patients: a randomized clinical trial. Int J Reprod BioMed. 2016;14(10):657–664. - PMC - PubMed
    1. Kalkhoran LF, Bahrami H, Farrokhi NA, Zeraati H, Tarahomi M. Comparing anxiety, depression and sexual life satisfaction in two groups of fertile and infertile women in Tehran. J Reprod Infertil. 2011;12(2):157-62.
    1. Direkvand Moghaddam A, Delpisheh A, Sayehmiri K. An investigation of the worldwide prevalence of infertility as a systematic review. Qom Univ Med Sci J. 2016;10(1):76–87.
    1. Parsanezhad ME, Jahromi BN, Zare N, Keramati P, Khalili A, Parsa-Nezhad M. Epidemiology and etiology of infertility in Iran, systematic review and meta-analysis. J Womens Health Issues Care. 2016;2(6):2013.
    1. Van den Broeck U, Emery M, Wischmann T, Thorn P. Counselling in infertility: individual, couple and group interventions. Patient Educ Couns. 2010;81(3):422–428. doi: 10.1016/j.pec.2010.10.009. - DOI - PubMed

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