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Review
. 2021 May 27:14:2181-2190.
doi: 10.2147/RMHP.S307150. eCollection 2021.

Environmental Pollution and Peripheral Artery Disease

Affiliations
Review

Environmental Pollution and Peripheral Artery Disease

Raffaele Serra et al. Risk Manag Healthc Policy. .

Abstract

Peripheral artery disease (PAD) of the lower limbs represents one of the most important clinical conditions among vascular disease and can negatively impact quality of life of affected patients, representing also an important socioeconomic burden. Several risk factors predispose to PAD and its complications. Nevertheless, the role of pollution in this context has not been fully evaluated and this article explored the most updated information on epidemiology and environmental pollution in order to hypothesize the possible contribution of air pollution in the onset of PAD. Pollution is an important problem for the global community and has harmful effects on human health and cardiovascular system, and, specifically, particulate matter 10 (PM10) was found significantly associated with PAD.

Keywords: PM10; environment; peripheral artery disease; pollution; risk factors.

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Conflict of interest statement

The authors reported no conflicts of interest for this work.

Figures

Figure 1
Figure 1
Correlation between PM10 and PAD.
Figure 2
Figure 2
Correlation between PM2.5 and PAD.
Figure 3
Figure 3
Correlation between BaP and PAD.

References

    1. Ielapi N, Licastro N, Catana M, Bracale UM, Serra R. Vascular nursing and vascular surgery. Ann Vasc Surg. 2020;68:522–526. doi:10.1016/j.avsg.2020.05.038 - DOI - PubMed
    1. Song P, Rudan D, Zhu Y, et al. Global, regional, and national prevalence and risk factors for peripheral artery disease in 2015: an updated systematic review and analysis. Lancet. 2019;7(8):e1020–e1030. - PubMed
    1. Rajagopalan S, Al-Kindi SG, Brook RD, Pollution A. Cardiovascular disease: JACC state-of-the-art review. J Am Coll Cardiol. 2018;72(17):2054–2070. doi:10.1016/j.jacc.2018.07.099 - DOI - PubMed
    1. Shammas NW. Epidemiology, classification, and modifiable risk factors of peripheral arterial disease. Vasc Health Risk Manag. 2007;3(2):229–234. doi:10.2147/vhrm.2007.3.2.229 - DOI - PMC - PubMed
    1. Newby DE, Mannucci PM, Tell GS, et al; Group on Thrombosis, European Association for Cardiovascular Prevention and Rehabilitation; ESC Heart Failure Association. Expert position paper on air pollution and cardiovascular disease. Eur Heart J. 2015;36(2):83–93b. - PMC - PubMed

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