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. 2021 May;76(5-6):419-424.

[Glioblastoma]

[Article in French]
D H Martin  1 , E Bianchi  2 , S Ben Mustapha  3 , P Frères  4
Affiliations
  • PMID: 34080374
Free article

[Glioblastoma]

[Article in French]
D H Martin et al. Rev Med Liege. 2021 May.
Free article

Abstract
in English, French

Glioblastoma is the most common primary malignant brain tumor. Despite treatments combining excisional surgery, chemotherapy, and radiotherapy, overall survival remains low and the incidence of tumor recurrence remains high. Advances in the understanding of the disease, particularly its molecular biology and the mechanisms of action of systemic and radiotherapeutic treatments, as well as the development of image-guided surgical techniques, offer hope for the control of this hitherto incurable disease.

Le glioblastome est la tumeur cérébrale maligne primitive la plus fréquente. Malgré des traitements combinant la chirurgie d’exérèse, la chimiothérapie et la radiothérapie, la survie globale reste faible avec une incidence élevée de récidive tumorale. Les progrès dans la compréhension de la maladie, et en particulier de la biologie moléculaire et des mécanismes d’action des traitements systémiques et radiothérapeutiques, de même que le développement des techniques chirurgicales guidées par l’image, permettent d’entrevoir un espoir dans le contrôle de cette maladie jusqu’ici incurable.

Keywords: IDH; MGMT; Radiotherapy; Surgery; Glioblastoma.

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