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Comparative Study
. 2021 Jun 3;22(1):210.
doi: 10.1186/s12882-021-02412-z.

Quality of life for kidney transplant recipients and hemodialysis patients in Palestine: a cross-sectional study

Adnan Lutfi Sarhan  1 , Raya H Jarareh  2 , Mujahed Shraim  3
Affiliations
Comparative Study

Quality of life for kidney transplant recipients and hemodialysis patients in Palestine: a cross-sectional study

Adnan Lutfi Sarhan et al. BMC Nephrol. .

Abstract

Background: Health related quality of life (HRQOL) is an important indicator of medical treatment and is a strong predictor of disability and mortality. The literature has shown mixed evidence about whether kidney transplantation improves HRQOL compared with other renal replacement modalities. The aim of this study was to compare the HRQOL in kidney transplant recipients (KTRs) and hemodialysis (HD) patients.

Methods: A cross-sectional study of 100 KTRs and 272 HD patients from two central kidney units in the West Bank, Palestine. The HRQOL was assessed using the Short Form-36 Health Survey. Multivariable linear regression was used to estimate differences in mean HRQOL scores between KTRs and HD patients.

Results: As compared to HD patients, KTRs had higher clinically important HRQOL in main domains and subscales of the SF-36 including physical functioning, role-physical, bodily pain, general health, vitality, social functioning, role-emotional, mental health, ranging between 15.5 for social functioning (95% Confidence Interval (CI) 10.1, 20.7) to 32.6 for general health (95% CI 24.0, 41.1).

Conclusions: We found that KTRs have better HRQOL than HD patients in physical and mental components of the SF-36 scale including physical functioning, role-physical, bodily pain, general health, vitality, social functioning, role-emotional, and mental health. Further longitudinal research comparing HRQOL among KTRs and the general population may identify key modifiable factors associated with lower HRQOL among KTRs that are amenable to intervention.

Keywords: Cross-sectional studies; Kidney transplantation; Quality of life; Renal Dialysis.

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Conflict of interest statement

The authors have no relevant financial or non-financial interests to disclose.

Figures

Fig. 1
Fig. 1
Unadjusted SF-36 mean scores in kidney transplant recipients (n = 100) and hemodialysis patients (n = 272). PF, Physical functioning; RP, Role-physical; BP, Bodily pain; GH, General health; VT, Vitality; SF, Social functioning; RE, Role-emotional; MH, Mental health; PCS, Physical component summary; MCS, Mental component summary
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