Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 2021 Jun 3;22(1):210.
doi: 10.1186/s12882-021-02412-z.

Quality of life for kidney transplant recipients and hemodialysis patients in Palestine: a cross-sectional study

Adnan Lutfi Sarhan  1 , Raya H Jarareh  2 , Mujahed Shraim  3
Affiliations
Comparative Study

Quality of life for kidney transplant recipients and hemodialysis patients in Palestine: a cross-sectional study

Adnan Lutfi Sarhan et al. BMC Nephrol. .

Abstract

Background: Health related quality of life (HRQOL) is an important indicator of medical treatment and is a strong predictor of disability and mortality. The literature has shown mixed evidence about whether kidney transplantation improves HRQOL compared with other renal replacement modalities. The aim of this study was to compare the HRQOL in kidney transplant recipients (KTRs) and hemodialysis (HD) patients.

Methods: A cross-sectional study of 100 KTRs and 272 HD patients from two central kidney units in the West Bank, Palestine. The HRQOL was assessed using the Short Form-36 Health Survey. Multivariable linear regression was used to estimate differences in mean HRQOL scores between KTRs and HD patients.

Results: As compared to HD patients, KTRs had higher clinically important HRQOL in main domains and subscales of the SF-36 including physical functioning, role-physical, bodily pain, general health, vitality, social functioning, role-emotional, mental health, ranging between 15.5 for social functioning (95% Confidence Interval (CI) 10.1, 20.7) to 32.6 for general health (95% CI 24.0, 41.1).

Conclusions: We found that KTRs have better HRQOL than HD patients in physical and mental components of the SF-36 scale including physical functioning, role-physical, bodily pain, general health, vitality, social functioning, role-emotional, and mental health. Further longitudinal research comparing HRQOL among KTRs and the general population may identify key modifiable factors associated with lower HRQOL among KTRs that are amenable to intervention.

Keywords: Cross-sectional studies; Kidney transplantation; Quality of life; Renal Dialysis.

PubMed Disclaimer

Conflict of interest statement

The authors have no relevant financial or non-financial interests to disclose.

Figures

Fig. 1
Fig. 1
Unadjusted SF-36 mean scores in kidney transplant recipients (n = 100) and hemodialysis patients (n = 272). PF, Physical functioning; RP, Role-physical; BP, Bodily pain; GH, General health; VT, Vitality; SF, Social functioning; RE, Role-emotional; MH, Mental health; PCS, Physical component summary; MCS, Mental component summary
See this image and copyright information in PMC

References

    1. Luyckx VA, Tonelli M, Stanifer JW. The global burden of kidney disease and the sustainable development goals. Bull World Health Organ. 2018;96(6):414–22D. doi: 10.2471/BLT.17.206441. - DOI - PMC - PubMed
    1. Couser WG, Remuzzi G, Mendis S, Tonelli M. The contribution of chronic kidney disease to the global burden of major noncommunicable diseases. Kidney Int. 2011;80(12):1258–1270. doi: 10.1038/ki.2011.368. - DOI - PubMed
    1. Hill NR, Fatoba ST, Oke JL, Hirst JA, O'Callaghan CA, Lasserson DS, et al. Global prevalence of chronic kidney disease - a systematic review and meta-analysis. PLoS One. 2016;11(7):e0158765. doi: 10.1371/journal.pone.0158765. - DOI - PMC - PubMed
    1. Babińska A, Wawrzynek W, Czech E, Skupiński J, Szczygieł J, Łabuz-Roszak B. No association between MRI changes in the lumbar spine and intensity of pain, quality of life, depressive and anxiety symptoms in patients with low back pain. Neurol Neurochir Pol. 2019;53(1):74–82. doi: 10.5603/PJNNS.a2018.0006. - DOI - PubMed
    1. Dalrymple LS, Katz R, Kestenbaum B, Shlipak MG, Sarnak MJ, Stehman-Breen C, Seliger S, Siscovick D, Newman AB, Fried L. Chronic kidney disease and the risk of end-stage renal disease versus death. J Gen Intern Med. 2011;26(4):379–385. doi: 10.1007/s11606-010-1511-x. - DOI - PMC - PubMed

Publication types